Reciprocal influence of connexins and apical junction proteins on their expressions and functions.
Reciprocal influence of connexins and apical junction proteins on their expressions and functions.
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DOI:
10.1016/j.bbamem.2008.10.023
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发表时间:
2009-04
影响因子:
3.4
通讯作者:
Herve, Jean-Claude
中科院分区:
文献类型:
--
作者:
Derangeon, Mickael;Spray, David C.;Bourmeyster, Nicolas;Sarrouilhe, Denis;Herve, Jean-Claude
Membranes of adjacent cells form intercellular junctional complexes to mechanically anchor neighbour cells (anchoring junctions), to seal the paracellular space and to prevent diffusion of integral proteins within the plasma membrane (tight junctions) and to allow cell-to-cell diffusion of small ions and molecules (gap junctions). These different types of specialised plasma membrane microdomains, sharing common adaptor molecules, particularly zonula occludens proteins, frequently present intermingled relationships where the different proteins co-assemble into macromolecular complexes and their expressions are co-ordinately regulated. Proteins forming gap junction channels (connexins, particularly) and proteins fulfilling cell attachment or forming tight junction strands mutually influence expression and functions of one another.
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影响因子:
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作者:
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通讯作者:
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DOI:
10.1073/pnas.0804793105
发表时间:
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