BRAIN ACTIVATION RELATED TO AFFECTIVE DIMENSION DURING THERMAL STIMULATION IN HUMANS: A FUNCTIONAL MAGNETIC RESONANCE IMAGING STUDY
BRAIN ACTIVATION RELATED TO AFFECTIVE DIMENSION DURING THERMAL STIMULATION IN HUMANS: A FUNCTIONAL MAGNETIC RESONANCE IMAGING STUDY
复制标题
人类热刺激期间与情感维度相关的大脑激活：功能磁共振成像研究
DOI：
10.1080/00207450600934432
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发表时间：
2007
影响因子：
2.2
通讯作者：
H. W. Park
中科院分区：
文献类型：
--
作者：
Eun;S. Yoo;H. Yoon;S. Oh;Yeji Han;H. W. Park
这项研究的目的是利用功能磁共振成像来识别与热刺激(不是疼痛，而是无害的升温)的情感维度有关的激活的大脑区域。12名健康、惯用右手的男性受试者参与了这项研究。受试者分别在41°C和34°C两种不同温度下进行热刺激，使用热刺激包包裹每个受试者的右小腿。根据受试者在扫描过程后的反应，作者能够观察到受试者在41°C的条件下感到“温暖”和“略带愉悦和舒适”。实验结果表明，热刺激在对侧岛叶、同侧小脑、同侧壳核、对侧额中回、同侧额下回、对侧中央后回和对侧中央旁小叶等部位的激活程度明显高于热中性刺激。已知的激活区域与热感觉、情感/情绪意识、认知功能、感觉辨别和情绪/情感加工等有关。这些结果表明，适当的热刺激可以产生积极的情绪，并激活情绪/影响大脑的相关区域。
The aim of this study was to identify the activated brain region that is involved with the affective dimension of thermal stimulation (not pain, but innocuous warming) using functional MR imaging. Twelve healthy, right-handed male subjects participated in the study. Thermal stimulation with two different temperatures of 41°C and 34°C was applied to the subjects using a fomentation pack, wrapped around the right lower leg of each subject. On the basis of the subjects’ responses after the scanning sessions, the authors were able to observe that the subjects felt “warm” and “slightly pleasant and comfortable” under the 41°C condition. The experimental results indicated that warm stimulation produced a significant increase of activation compared to thermal neutral stimulation in various regions such as contralateral insular, ipsilateral cerebellum, ipsilateral putamen, contralateral middle frontal gyrus, ipsilateral inferior frontal gyrus, contralateral postcentral gyrus, and contralateral paracentral lobule. The activated regions are known to be related to thermal sensory, affective/emotional awareness, cognitive functions, sensory-discrimination, and emotion/affective processing, and so on. These results suggest that an appropriate thermal stimulation can produce a positive emotion and activate emotion/affect related regions of the brain.
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影响因子：
14.5
作者：
Cohen, MS;Kosslyn, SM;Belliveau, JW
通讯作者：
Belliveau, JW
影响因子：
0.9
作者：
APKARIAN, AV;STEA, RA;BOLANOWSKI, SJ
通讯作者：
BOLANOWSKI, SJ
影响因子：
7.6
作者：
TOMARKEN, AJ;DAVIDSON, RJ;DOSS, RC
通讯作者：
DOSS, RC
影响因子：
2.5
作者：
Apkarian, AV;Darbar, A;Szeverenyi, NM
通讯作者：
Szeverenyi, NM