Sub-millimeter isotropic MRI for segmentation of subcortical brain regions and brain visualization.
Sub-millimeter isotropic MRI for segmentation of subcortical brain regions and brain visualization.
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DOI：
10.1002/jmri.22120
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发表时间：
2010-04
影响因子：
4.4
通讯作者：
Edelman, Robert R.
中科院分区：
文献类型：
--
作者：
Wu, Ying;Ragin, Ann B.;Du, Hongyan;Sidharthan, Shawn;Dunk, Eugene E.;Koktzoglou, Ioannis;Edelman, Robert R.
我们评估了一种快速亚毫米各向同性SPGR(非选择性SPGR)，以促进大脑皮质下分割和脑体积的可视化，并与普遍接受的SPGR-IR技术进行了比较。对两种分割算法的非选择性SPGR的可行性进行了评估。FAST用于将大脑分割成不同的组织类别(白质、灰质、脑脊液)，Freesurfer用于分割特定的皮质下结构(海马、尾状核、壳核和丘脑)。比较非选择性SPGR和SPGR-IR在所研究的皮质下区域的局部表观SNR和CNR值。采用三维体绘制技术对非选择性SPGR和SPGR-IR进行脑可视化评价。在基底节区域，非选择性SPGR允许快速和自由浏览的一致分割结果。与SPGR-IR相比，该序列还能更好地区分灰质/白质。对于皮质下解剖结构，与SPGR-IR相比，使用非选择性SPGR的图像质量在表观SNR和CNR方面大约提高了两倍。与SPGR-IR相比，非选择性SPGR提高了清晰度，并为可视化提供了更逼真的脑表面描述。与SPGR-IR相比，非选择性SPGR能够对基底节区域进行一致的分割，并提高了大脑可视化的清晰度。
We evaluated a rapid sub-millimeter isotropic SPGR (non-selective SPGR) to facilitate the brain subcortical segmentation and the visualization of brain volume compared with the commonly-accepted SPGR-IR technique. The feasibility of the non-selective SPGR was evaluated for two segmentation algorithms. FAST was used to segment the brain into constituent tissue classes (white matter, gray matter, CSF) and FreeSurfer was used to segment specific subcortical structures (hippocampus, caudate, putamen and thalamus). Localized apparent SNR and CNR values for non-selective SPGR and the SPGR-IR were compared for the studied subcortical regions. 3D volume rendering was generated to evaluate the non-selective SPGR and the SPGR-IR for brain visualization. In basal ganglia regions, non-selective SPGR allows for consistent segmentation results for both FAST and FreeSurfer. This sequence also better differentiated grey/white matter compared to SPGR-IR. An approximate two-fold improvement of image quality in apparent SNR and CNR was indicated for subcortical brain anatomical structures with non-selective SPGR versus SPGR-IR. The non-selective SPGR improved clarity and yielded a more realistic depiction of the brain surface for visualization compared with SPGR-IR. Compared with SPGR-IR, non-selective SPGR allows for consistent segmentation results for basal ganglia regions and improved clarity for visualization of brain.
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影响因子：
--
作者：
Aylward, EH;Codori, AM;Brandt, J
通讯作者：
Brandt, J
影响因子：
4.8
作者：
Smith, SM
通讯作者：
Smith, SM
影响因子：
6.7
作者：
Edelman, Robert R.;Dunkle, Eugene;Carrillo, Andres
通讯作者：
Carrillo, Andres
影响因子：
11
作者：
Molyneux, PD;Tofts, PS;Miller, DH
通讯作者：
Miller, DH
影响因子：
5.7
作者：
Hua X;Leow AD;Parikshak N;Lee S;Chiang MC;Toga AW;Jack CR Jr;Weiner MW;Thompson PM;Alzheimer's Disease Neuroimaging Initiative
通讯作者：
Alzheimer's Disease Neuroimaging Initiative