Virology: SARS virus infection of cats and ferrets.

Virology: SARS virus infection of cats and ferrets.
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DOI:
10.1038/425915a
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发表时间:
2003-10-30
期刊:
影响因子:
64.8
通讯作者:
Osterhaus AD
Osterhaus AD
中科院分区:
综合性期刊1区
文献类型:
--
作者:
Martina BE;Haagmans BL;Kuiken T;Fouchier RA;Rimmelzwaan GF;Van Amerongen G;Peiris JS;Lim W;Osterhaus AD

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现在可以选择动物模型来测试针对人类病毒的疗法。本文的在线版本(doi:10.1038/425915 a)包含补充材料,可供授权用户使用。从严重急性呼吸道综合征(SARS)患者身上分离出的冠状病毒的宿主仍然未知,但怀疑是一种野生动物。在这里,我们表明,雪貂(Mustela furo)和家猫(Felis arteriticus)容易受到SARS冠状病毒(SCV)的感染,它们可以有效地将病毒传播给以前未感染的动物,这些动物与它们一起饲养。观察到这两种关系遥远的食肉动物可以如此容易地感染病毒,表明这种病原体的宿主可能涉及一系列动物物种。本文的在线版本(doi:10.1038/425915 a)包含补充材料,可供授权用户使用。
There is now a choice of animal models for testing therapies against the human virus. The online version of this article (doi:10.1038/425915a) contains supplementary material, which is available to authorized users. The reservoir of the coronavirus isolated from patients with severe acute respiratory syndrome (SARS) is still unknown, but is suspected to have been a wild animal species. Here we show that ferrets (Mustela furo) and domestic cats (Felis domesticus) are susceptible to infection by SARS coronavirus (SCV) and that they can efficiently transmit the virus to previously uninfected animals that are housed with them. The observation that these two distantly related carnivores can so easily be infected with the virus indicates that the reservoir for this pathogen may involve a range of animal species. The online version of this article (doi:10.1038/425915a) contains supplementary material, which is available to authorized users.
DOI: 10.1016/s0140-6736(03)13077-2
发表时间: 2003-04-19
期刊: Lancet (London, England)
影响因子: --
作者:
Peiris JS;Lai ST;Poon LL;Guan Y;Yam LY;Lim W;Nicholls J;Yee WK;Yan WW;Cheung MT;Cheng VC;Chan KH;Tsang DN;Yung RW;Ng TK;Yuen KY;SARS study group
通讯作者: SARS study group
DOI: 10.1016/s0140-6736(03)13967-0
发表时间: 2003-07-26
期刊: Lancet (London, England)
影响因子: --
作者:
Kuiken T;Fouchier RA;Schutten M;Rimmelzwaan GF;van Amerongen G;van Riel D;Laman JD;de Jong T;van Doornum G;Lim W;Ling AE;Chan PK;Tam JS;Zambon MC;Gopal R;Drosten C;van der Werf S;Escriou N;Manuguerra JC;Stöhr K;Peiris JS;Osterhaus AD
通讯作者: Osterhaus AD
DOI: 10.1126/science.1087139
发表时间: 2003-10-10
期刊: SCIENCE
影响因子: 56.9
作者:
Guan, Y;Zheng, BJ;Poon, LLM
通讯作者: Poon, LLM
DOI: 10.1056/nejmoa030781
发表时间: 2003-05-15
影响因子: 158.5
作者:
Ksiazek, TG;Erdman, D;Anderson, LJ
通讯作者: Anderson, LJ
Aetiology:Koch的假设对SARS病毒实现。
DOI: 10.1038/423240a
发表时间: 2003-05-15
期刊: Nature
影响因子: 64.8
作者:
Fouchier RA;Kuiken T;Schutten M;van Amerongen G;van Doornum GJ;van den Hoogen BG;Peiris M;Lim W;Stöhr K;Osterhaus AD
通讯作者: Osterhaus AD