A scoping review of how early-stage knee osteoarthritis has been defined.
A scoping review of how early-stage knee osteoarthritis has been defined.
复制标题
早期膝关节骨关节炎定义的范围综述。
DOI：
10.1016/j.joca.2023.04.015
复制
发表时间：
2023-09
影响因子：
7
通讯作者：
Hawker, Gillian
中科院分区：
文献类型：
--
作者：
Liew, Jean W.;King, Lauren K.;Mahmoudian, Armaghan;Wang, Qiuke;Atkinson, Hayden F.;Flynn, David B.;Appleton, C. Thomas;Englund, Martin;Haugen, Ida K.;Lohmander, L. Stefan;Runhaar, Jos;Neogi, Tuhina;Hawker, Gillian
关键词：
Early-stage knee osteoarthritis (KOA) classification criteria will enable consistent identification and trial recruitment of individuals with knee OA at an earlier stage of disease, when interventions may be more effective. Towards this goal, we identified how early-stage KOA has been defined in the literature. We performed a scoping literature review in PubMed, EMBASE, Cochrane, and Web of Science including human studies where early-stage KOA was included as a study population or outcome. Extracted data included demographics, symptoms/history, examination, laboratory, imaging, performance-based measures, and gross inspection/histopathologic domains, and the components of composite early-stage KOA definitions. Of 6142 articles identified, 211 were included in data synthesis. An early-stage KOA definition was used for study inclusion in 194 studies, to define study outcome in 11 studies, and in the context of new criteria development or validation in 6 studies. The element most often used to define early-stage KOA was Kellgren-Lawrence (KL) grade (151 studies, 72%), followed by symptoms (118 studies, 56%) and demographic characteristics (73 studies, 35%); 14 studies (6%) used previously developed early-stage KOA composite criteria. Among studies defining early-stage KOA radiographically, 52 studies defined early-stage KOA by KL grade alone; of these 52, 44 (85%) studies included individuals with KL grade 2 or higher in their definitions. Early-stage KOA is variably defined in the published literature. Most studies included KL grades of 2 or higher within their definitions, which reflects established or later-stage OA. These findings underscore the need to develop and validate classification criteria for early-stage KOA.
登录
查看更多内容
影响因子：
7
作者：
Roemer, F. W.;Felson, D. T.;Stefanik, J. J.;Rabasa, G.;Wang, N.;Crema, M. D.;Neogi, T.;Nevitt, M. C.;Torner, J.;Lewis, C. E.;Peloquin, C.;Guermazi, A.
通讯作者：
Guermazi, A.
影响因子：
5
作者：
Wang, Qiuke;Runhaar, Jos;Bierma-Zeinstra, Sita M. A.
通讯作者：
Bierma-Zeinstra, Sita M. A.
影响因子：
27.4
作者：
Wesseling, J.;Dekker, J.;Bijlsma, J. W. J.
通讯作者：
Bijlsma, J. W. J.
DOI：
10.1093/rheumatology/keaa643
发表时间：
2021-05-14
期刊：
Rheumatology (Oxford, England)
影响因子：
--
作者：
Runhaar J;Kloppenburg M;Boers M;Bijlsma JWJ;Bierma-Zeinstra SMA;the CREDO expert group
通讯作者：
the CREDO expert group
影响因子：
39.2
作者：
Tricco, Andrea C.;Lillie, Erin;Straus, Sharon E.
通讯作者：
Straus, Sharon E.