Xanthophore migration from the dermis to the epidermis and dermal remodeling during Salamandra salamandra salamandra (L.) larval development.
Xanthophore migration from the dermis to the epidermis and dermal remodeling during Salamandra salamandra salamandra (L.) larval development.
复制标题
蝾螈 (L.) 幼虫发育过程中黄素从真皮迁移到表皮和真皮重塑。
DOI：
10.1034/j.1600-0749.2003.00013.x
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发表时间：
2003
期刊：
影响因子：
--
通讯作者：
C. Restani
中科院分区：
文献类型：
--
作者：
A. Pederzoli;A. Gambarelli;C. Restani
在Salamandra salamandra的幼虫发育过程中，Salamandra色素细胞组织形成由黑色背景和黄色斑块构成的确定的色素图案，其特征在于表皮黄色素细胞和真皮虹膜色素细胞。同时，真皮经历从幼虫阶段到典型的成虫阶段的重塑。在本研究中，我们超微结构和免疫细胞化学检查皮肤碎片的S。S.为了研究在从幼虫到成虫阶段的皮肤重塑的背景下，黄色素细胞迁移和分化的方式，对蝾螈幼虫和幼虫进行了研究。半薄切片和薄切片显示，新生幼虫的真皮由致密的结缔组织（基底层）和松散的深层胶原蛋白层组成，成纤维细胞和黄色素细胞粘附在基底层上。随着幼虫发育的进行，成纤维细胞和黄色素细胞侵入基底层，皮肤腺体发育，成虫真皮形成。在变态时，黄色素细胞穿过基膜到达表皮。我们研究了免疫细胞化学的信号分子，如纤连蛋白，玻连蛋白，β 1-整合素，硫酸软骨素，E-钙粘蛋白，N-钙粘蛋白和纤溶酶原激活剂，这是已知的参与调节形态发生事件的表达。他们的作用在真皮重塑和色素模式的形成进行了讨论。
During larval development of Salamandra salamandra salamandra chromatophores organize to form the definitive pigment pattern constituted by a black background with yellow patches that are characterized by epidermal xanthophores and dermal iridophores. Simultaneously the dermis undergoes remodeling from the larval stage to that typical of the adult. In the present study we ultrastucturally and immunocytochemically examined skin fragments of S. s. salamandra larvae and juveniles in order to investigate the modalities of xanthophore migration and differentiation in the context of dermal remodeling from the larval to adult stage. Semithin and thin sections showed that the dermis in newly born larvae consists of a compact connective tissue (basement lamella), to which fibroblasts and xanthophores adhere, and of a loose deep collagen layer. As larval development proceeds, fibroblasts and xanthophores invade the basement lamella, skin glands develop and the adult dermis forms. At metamorphosis, xanthophores reach the epidermis crossing through the basal lamina. We examined immunocytochemically the expression of signal molecules, such as fibronectin, vitronectin, beta1-integrin, chondroitin sulfate, E-cadherin, N-cadherin and plasminogen activator, which are known to be involved in regulating morphogenetic events. Their role in dermal remodeling and in pigment pattern formation is discussed.
影响因子：
4.6
作者：
M. Delannet;F. Martin;B. Bossy;D. Cheresh;L. F. Reichardt;J. Duband
通讯作者：
M. Delannet;F. Martin;B. Bossy;D. Cheresh;L. F. Reichardt;J. Duband
纤溶酶原激活剂活性与组织培养中的神经嵴细胞运动相关。
DOI：
10.1002/jez.1402510203
发表时间：
1989
期刊：
The Journal of experimental zoology
影响因子：
--
作者：
Erickson,CA;Isseroff,RR
通讯作者：
Isseroff,RR
胶原纤维在发育中的真皮中组装和沉积：细胞外区室中的节段沉积。
影响因子：
3
作者：
Ploetz,C;Zycband,EI;Birk,DE
通讯作者：
Birk,DE