Quality Control of Radix Astragali (The Root of Astragalus membranaceus var. mongholicus) Along Its Value Chains.

Quality Control of Radix Astragali (The Root of Astragalus membranaceus var. mongholicus) Along Its Value Chains.
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Radix Astragali(Astragalus膜的根部山地)沿其价值链的质量控制。

DOI:
10.3389/fphar.2020.562376
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发表时间:
2020
影响因子:
5.6
通讯作者:
Li M
Li M
中科院分区:
医学2区
文献类型:
--
作者:
Bi Y;Bao H;Zhang C;Yao R;Li M

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黄芪(Radix Astragali, RA)是黄芪(Astragalus aceus var. mongholicus, Bunge) P.K. Hsiao的根,在中国被用作传统草药或食品已有2000多年的历史,现在全球都在消费。不幸的是,对RA需求的增加导致了其野生种群的过度开发,以及掺假和污染等质量问题。因此,迫切需要RA的可持续栽培。在本研究中,通过半结构化访谈和关键信息提供者访谈,在2年的时间里,从主要生产区域的利益相关者那里收集数据;此外,采用基于化学分析的针对性质量评价策略,了解RA的质量。据此,在RA生产中确定了10种不同类型的价值链;同时,采用HPLC-ELSD-UV分析黄芪甲苷和毛蕊花苷-7- o -β- d -葡萄糖苷的含量,测定药材得率,并采用k-means聚类分析。研究结果表明,风险投资公司的风险投资质量与利益相关者的收益之间存在密切的关系,这反映了生产系统中更普遍的趋势。在过去的几十年里,垂直协调在RA的风险投资中越来越多地出现,这导致了供应链中更连贯的可追溯性系统和严格的法规。道地草药可以被认为是一种标准,具有鲜明的品质特征,强调药用植物的起源。研究发现,地理区域的适宜性和垂直整合可以提高RA的风险投资,从而有助于其质量控制和可持续生产。
Radix Astragali (RA), the root of Astragalus membranaceus var. mongholicus (Bunge) P.K. Hsiao, known as “Huangqi” in Chinese, has been used as a traditional herbal medicine or food in China for more than 2,000 years and is now consumed globally. Unfortunately, the increasing demand for RA has led to the overexploitation of its wild stock, as well as quality problems, including adulteration and contamination. Therefore, the sustainable cultivation of RA is urgently needed. In the present research, semi-structured interviews and key informant interviews were conducted, over a 2-year period, to collect data from stakeholders in the main production areas; moreover, a targeted chemical analysis-based quality assessment strategy was applied to understand the quality of RA. Accordingly, 10 different types of value chains (VCs) were identified in RA production; meanwhile, the contents of the main active ingredients (astragaloside and calycosin-7-O-β-D-glucoside) were analyzed by HPLC-ELSD-UV and the yield of medicinal material was demined and further analyzed using k-means clustering analysis. The results show that the tight relationship between quality of the RA and stakeholders’ revenues among the VCs, which reflects a more general trend in the production system. Over the past few decades, vertical coordination has emerged increasingly in VCs of RA, which leads to a more coherent traceability system and rigorous regulations in the supply chains. Daodi herbs can be considered to be a standard that is distinctive with good quality characteristics that emphasize the origins of the medicinal plants. We find that the suitability of geographical areas and vertical integration can improve the VCs of RA, which further contributes to its quality control, as well as its sustainable production.
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