Prevalence and burden of chronic kidney disease among the general population and high-risk groups in Africa: a systematic review.
Prevalence and burden of chronic kidney disease among the general population and high-risk groups in Africa: a systematic review.
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非洲普通人群和高风险群体中慢性肾脏疾病的患病率和负担：系统评价。
DOI：
10.1136/bmjopen-2016-015069
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发表时间：
2018-01-10
期刊：
影响因子：
2.9
通讯作者：
Zoccali C
中科院分区：
文献类型：
--
作者：
Abd ElHafeez S;Bolignano D;D'Arrigo G;Dounousi E;Tripepi G;Zoccali C
虽然人们越来越关注非洲慢性病患病率的上升，但对慢性肾脏病（CKD）的关注很少。这项系统性综述评估了整个非洲大陆普通人群和高危人群的CKD负担。我们通过敏感检索策略检索了Medline和PubMed数据库中1995年1月1日至2017年4月7日期间发表的文章，重点关注社区水平和高危人群的CKD调查。共评价了7918篇参考文献，其中7766篇文献因不符合纳入标准而被排除。因此，152项研究被纳入最终分析。每个研究组中CKD的患病率表示为范围，CKD的合并患病率计算为点估计值和95% CI。未进行荟萃分析。提供了不同人群的数据。在社区水平研究中，基于现有的中等质量和高质量研究，CKD的患病率范围为2%至41%（合并患病率：10.1%; 95% CI 9.8%至10.5%）。CKD在高危人群中的患病率范围为1%至46%（合并患病率：5.6%; 95% CI 5.4%-5.8%）（根据现有的中等质量和高质量研究），11%-90%（合并患病率：24.7%; 95%CI 23.6%至25.7%）（根据所有现有的研究，除四项研究的质量中等外，其余研究的质量均较低）和13%-51%（合并患病率：34.5%; 95% CI 34.04%至36%）（基于所有现有的低质量研究，除两项中等质量研究外）。在非洲，CKD是一个公共卫生问题，主要归因于高血压和糖尿病等高危疾病。较差的数据质量限制了研究结果的有效性，并提请注意设计未来稳健研究的重要性。
While increasing attention is paid to the rising prevalence of chronic diseases in Africa, there is little focus on chronic kidney disease (CKD). This systematic review assesses CKD burden among the general population and high-risk groups on the entire African continent. We searched Medline and PubMed databases for articles published between 1 January 1995 and 7 April 2017 by sensitive search strategies focusing on CKD surveys at the community level and high-risk groups. In total, 7918 references were evaluated, of which 7766 articles were excluded because they did not meet the inclusion criteria. Thus, 152 studies were included in the final analysis. The prevalence of CKD in each study group was expressed as a range and pooled prevalence rate of CKD was calculated as a point estimate and 95% CI. No meta-analysis was done. Data were presented for different populations. In the community-level studies, based on available medium-quality and high-quality studies, the prevalence of CKD ranged from 2% to 41% (pooled prevalence: 10.1%; 95% CI 9.8% to 10.5%). The prevalence of CKD in the high-risk groups ranged from 1% to 46% (pooled prevalence: 5.6%; 95% CI 5.4% to 5.8%) in patients with HIV (based on available medium-quality and high-quality studies), 11%–90% (pooled prevalence: 24.7%; 95% CI 23.6% to 25.7%) in patients with diabetes (based on all available studies which are of low quality except four of medium quality) and 13%–51% (pooled prevalence: 34.5%; 95 % CI 34.04% to 36%) in patients with hypertension (based on all available studies which are of low quality except two of medium quality). In Africa, CKD is a public health problem, mainly attributed to high-risk conditions as hypertension and diabetes. The poor data quality restricts the validity of the findings and draws the attention to the importance of designing future robust studies.
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影响因子：
6
作者：
Gupta SK;Ong'or WO;Shen C;Musick B;Goldman M;Wools-Kaloustian K
通讯作者：
Wools-Kaloustian K
影响因子：
1
作者：
Afolabi, M. O.;Abioye-Kuteyi, E. A.;Bello
通讯作者：
Bello
DOI：
10.1177/2325957415587570
发表时间：
2015-09-01
影响因子：
--
作者：
Adedeji, Tewogbade Adeoye;Adedeji, Nife O;Jimoh, Kayode A
通讯作者：
Jimoh, Kayode A
影响因子：
5.2
作者：
Adebamowo, Sally N.;Adeyemo, Adebowale A.;Rotimi, Charles N.
通讯作者：
Rotimi, Charles N.
影响因子：
0.8
作者：
Anyabolu, E N;Chukwuonye, I I;Ulasi, I
通讯作者：
Ulasi, I