Metabolic hypertension: concept and practice

Metabolic hypertension: concept and practice
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代谢性高血压:概念与实践

DOI:
10.1007/s11684-013-0264-4
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发表时间:
2013-04
影响因子:
8.1
通讯作者:
Ma, Shuangtao
Ma, Shuangtao
中科院分区:
医学1区
文献类型:
--
作者:
Zhu, Zhiming;Wang, Peijian;Ma, Shuangtao

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高血压是一个严重的全球性公共卫生问题。超过60%的高血压危险因素与代谢紊乱有关。代谢异常会增加高血压的风险,并导致高血压。改善代谢紊乱有利于高血压的治疗。鉴于代谢异常在高血压发病机制中的重要性,我们提出代谢性高血压的概念。本文就代谢性高血压的临床类型、发病机制、危险性评估及治疗进行综述。阐明代谢性高血压的机制有助于设计新的药物治疗和专门的抗高血压操作。
Hypertension is a serious public health problem worldwide. More than 60% of the risk factors for hypertension are associated with metabolic disturbances. Metabolic abnormalities increase the risk for hypertension and cause high blood pressure. Improving metabolic disturbances is beneficial for hypertension treatment. Due to the importance of metabolic abnormalities in the pathogenesis of hypertension, we propose a concept of metabolic hypertension. In this review, we discuss and review the clinical types, pathogenesis, risk evaluation and management of metabolic hypertension. Elucidation of the mechanism of metabolic hypertension should facilitate the design of novel pharmacotherapeutics and dedicated antihypertensive manipulations.
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