Patterns of Activity in the Human Frontal and Parietal Cortex Differentiate Large and Small Saccades.

Patterns of Activity in the Human Frontal and Parietal Cortex Differentiate Large and Small Saccades.
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DOI:
10.3389/fnint.2016.00034
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发表时间:
2016
影响因子:
3.5
通讯作者:
Grosbras MH
Grosbras MH
中科院分区:
医学3区
文献类型:
--
作者:
Grosbras MH

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大量的文献表明,小和大的眼跳,分别subserve不同的感知和认知策略,并可能依赖于不同的编程模式。虽然已经确定在猴子的主要眼脑区域中,小的和大的眼球运动是由分离的神经元群体控制的,但人类大脑中的扫视幅度的表示仍然不清楚。为了解决这个问题,我们使用功能性磁共振成像来扫描参与者,同时他们以短(4°)或大(30°)的偏心率对目标进行扫视。区域多体素模式分析表明,在额叶眼场和顶叶眼场的活动模式区分执行大或小扫视。这是不是在补充眼领域的情况下,也在下中央前皮质。这些研究结果提供了第一个证据的代表性扫视眼球运动的大小在额顶叶眼回路。他们阐明了不同皮质眼区在空间感知和探索方面的各自作用,以及人类和非人类灵长类动物之间眼动控制的同源性。
A vast literature indicates that small and large saccades, respectively, subserve different perceptual and cognitive strategies and may rely on different programming modes. While it is well-established that in monkeys’ main oculomotor brain regions small and large eye movements are controlled by segregated neuronal populations, the representation of saccade amplitude in the human brain remains unclear. To address this question we used functional magnetic resonance imaging to scan participants while they performed saccades toward targets at either short (4°) or large (30°) eccentricity. A regional multivoxel pattern analysis reveals that patterns of activity in the frontal eye-field and parietal eye fields discriminate between the execution of large or small saccades. This was not the case in the supplementary eye-fields nor in the inferior precentral cortex. These findings provide the first evidence of a representation of saccadic eye movement size in the fronto-parietal occulomotor circuit. They shed light on the respective roles of the different cortical oculomotor regions with respect to space perception and exploration, as well as on the homology of eye movement control between human and non-human primates.
DOI: 10.1162/089892902320474553
发表时间: 2002-10-01
影响因子: 3.2
作者:
Grosbras, MH;Paus, T
通讯作者: Paus, T
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