Food Fight: Role of Itaconate and Other Metabolites in Antimicrobial Defense.
Food Fight: Role of Itaconate and Other Metabolites in Antimicrobial Defense.
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DOI:
10.1016/j.cmet.2016.08.013
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发表时间:
2016-09-13
期刊:
影响因子:
29
通讯作者:
Medzhitov R
中科院分区:
文献类型:
--
作者:
Luan HH;Medzhitov R
Itaconate is a newly discovered mammalian metabolite bearing significant implications for our understanding of cellular immunometabolism and anti-microbial defense. Here, we explore recent findings regarding the role of itaconate in the innate immune response and highlight the emerging principle that metabolites can have distinct immunological functions independent of bioenergetics.
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影响因子:
30.5
作者:
通讯作者:
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影响因子:
30.5
作者:
通讯作者:
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影响因子:
20.3
作者:
Everts, Bart;Amiel, Eyal;Pearce, Edward J.
通讯作者:
Pearce, Edward J.
DOI:
10.1073/pnas.1404271111
发表时间:
2014-07-22
影响因子:
11.1
作者:
Gold, Elizabeth S.;Diercks, Alan H.;Aderem, Alan
通讯作者:
Aderem, Alan
影响因子:
3.7
作者:
Chiang EY;Johnston RJ;Grogan JL
通讯作者:
Grogan JL