Risk of second primary malignancy in adults with pulmonary high-grade neuroendocrine carcinoma (HGNEC)
Risk of second primary malignancy in adults with pulmonary high-grade neuroendocrine carcinoma (HGNEC)
复制标题
成人肺高级别神经内分泌癌 (HGNEC) 发生第二原发恶性肿瘤的风险
DOI:
10.1186/s12885-020-07224-2
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发表时间:
2020-08
期刊:
影响因子:
3.8
通讯作者:
Ping Chen
中科院分区:
文献类型:
--
作者:
Xiaomin Wu;Xiaojing Zhang;Leilei Tao;Ping Chen
BackgroundPulmonary high-grade neuroendocrine carcinoma (HGNEC) has a rising incidence of developing second primary malignancies (SPMs). This study is the first population-based analysis to quantify the SPM risks among survivors of lung HGNEC.MethodsWe used the Surveillance, Epidemiology, and End Results (SEER) database to calculate standardized incidence ratio (SIR) and absolute excess risk (AER) between 2000 and 2016 for patients with pulmonary HGNEC.ResultsThe data of 1161 patients with SPMs were retrieved from the SEER database. The ratio of observed/expected number of SPMs in pulmonary HGNEC was 1.53. Solid tumours comprised 91% of all second malignancies in lung HGNEC patients, with the most common cancers reported in the oral cavity and pharynx, the urinary and respiratory systemsConclusionsOur study observed an increased risk of SPMs among patients with pulmongnancies.
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影响因子:
5.3
作者:
通讯作者:
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影响因子:
4.6
作者:
Wang S;Tang J;Sun T;Zheng X;Li J;Sun H;Zhou X;Zhou C;Zhang H;Cheng Z;Ma H;Sun H
通讯作者:
Sun H
影响因子:
3.7
作者:
Yao Y;Gu X;Zhu J;Yuan D;Song Y
通讯作者:
Song Y
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16.6
作者:
George J;Walter V;Peifer M;Alexandrov LB;Seidel D;Leenders F;Maas L;Müller C;Dahmen I;Delhomme TM;Ardin M;Leblay N;Byrnes G;Sun R;De Reynies A;McLeer-Florin A;Bosco G;Malchers F;Menon R;Altmüller J;Becker C;Nürnberg P;Achter V;Lang U;Schneider PM;Bogus M;Soloway MG;Wilkerson MD;Cun Y;McKay JD;Moro-Sibilot D;Brambilla CG;Lantuejoul S;Lemaitre N;Soltermann A;Weder W;Tischler V;Brustugun OT;Lund-Iversen M;Helland Å;Solberg S;Ansén S;Wright G;Solomon B;Roz L;Pastorino U;Petersen I;Clement JH;Sänger J;Wolf J;Vingron M;Zander T;Perner S;Travis WD;Haas SA;Olivier M;Foll M;Büttner R;Hayes DN;Brambilla E;Fernandez-Cuesta L;Thomas RK
通讯作者:
Thomas RK
影响因子:
45.3
作者:
Dores, GM;Metayer, C;Travis, LB
通讯作者:
Travis, LB