Altered Effective Connectivity of Resting-State Networks by Tai Chi Chuan in Chronic Fatigue Syndrome Patients: A Multivariate Granger Causality Study.
Altered Effective Connectivity of Resting-State Networks by Tai Chi Chuan in Chronic Fatigue Syndrome Patients: A Multivariate Granger Causality Study.
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DOI：
10.3389/fneur.2022.858833
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发表时间：
2022
影响因子：
3.4
通讯作者：
Li, Kuangshi
中科院分区：
文献类型：
--
作者：
Li, Yuanyuan;Wu, Kang;Hu, Xiaojie;Xu, Tianjiao;Li, Zongheng;Zhang, Yong;Li, Kuangshi
大量证据表明，慢性疲劳综合征（CFS）患者静息时大脑功能连接发生改变，但目前尚无太极拳干预CFS的脑网络效应研究。为了探讨太极拳运动对慢性疲劳综合症患者脑功能网络之间因果关系的影响，招募21名慢性疲劳综合症患者和19名健康对照者在太极拳训练1个月之前和之后进行静息态功能磁共振成像（rs-fMRI）扫描和36项简表健康调查（SF-36）量表评估。我们采用独立成分分析（ICA）方法提取静息大脑网络，分析这些网络中FC的变化，对其进行格兰杰因果分析（GCA），并分析差异因果关系值与SF-36量表之间的相关性。与健康对照组相比，CFS 患者的 SF-36 量表评分在基线时较低。同时，感觉运动网络（SMN）与默认模式网络（DMN）之间的因果关系被削弱。上述异常可通过太极拳训练1个月得到改善。此外，相关性分析显示，SMN与DMN之间的因果关系与CFS患者的角色身体（RP）和身体疼痛（BP）评分呈正相关，且训练前后SMN与DMN因果关系的变化与BP评分的变化呈正相关。研究结果表明，太极拳有助于改善慢性疲劳综合症患者的生活质量。 SMN和DMN之间格兰杰因果关系的变化可能是CFS的读出参数。太极拳可能通过调节慢性疲劳综合症患者大脑网络之间的信息传递来促进其功能可塑性。
Numerous evidence has shown that patients with chronic fatigue syndrome (CFS) have changes in resting brain functional connectivity, but there is no study on the brain network effect of Tai Chi Chuan intervention in CFS. To explore the influence of Tai Chi Chuan exercise on the causal relationship between brain functional networks in patients with CFS, 21 patients with CFS and 19 healthy controls were recruited for resting-state functional magnetic resonance imaging (rs-fMRI) scanning and 36-item Short-Form Health Survey (SF-36) scale assessment before and after 1month-long training in Tai Chi Chuan. We extracted the resting brain networks using the independent component analysis (ICA) method, analyzed the changes of FC in these networks, conducted Granger causality analysis (GCA) on it, and analyzed the correlation between the difference causality value and the SF-36 scale. Compared to the healthy control group, the SF-36 scale scores of patients with CFS were lower at baseline. Meanwhile, the causal relationship between sensorimotor network (SMN) and default mode network (DMN) was weakened. The above abnormalities could be improved by Tai Chi Chuan training for 1 month. In addition, the correlation analyses showed that the causal relationship between SMN and DMN was positively correlated with the scores of Role Physical (RP) and Bodily Pain (BP) in CFS patients, and the change of causal relationship between SMN and DMN before and after training was positively correlated with the change of BP score. The findings suggest that Tai Chi Chuan is helpful to improve the quality of life for patients with CFS. The change of Granger causality between SMN and DMN may be a readout parameter of CFS. Tai Chi Chuan may promote the functional plasticity of brain networks in patients with CFS by regulating the information transmission between them.
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DOI：
10.1177/1073858411403316
发表时间：
2012-06
期刊：
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry
影响因子：
--
作者：
Andrews-Hanna JR
通讯作者：
Andrews-Hanna JR
影响因子：
4.4
作者：
Avellaneda Fernández A;Pérez Martín A;Izquierdo Martínez M;Arruti Bustillo M;Barbado Hernández FJ;de la Cruz Labrado J;Díaz-Delgado Peñas R;Gutiérrez Rivas E;Palacín Delgado C;Rivera Redondo J;Ramón Giménez JR
通讯作者：
Ramón Giménez JR
影响因子：
5.7
作者：
Havlicek M;Jan J;Brazdil M;Calhoun VD
通讯作者：
Calhoun VD
影响因子：
4.7
作者：
Bourke, Julius H.;Wodehouse, Theresa;White, Peter D.
通讯作者：
White, Peter D.
影响因子：
48
作者：
Esteban, Oscar;Markiewicz, Christopher J.;Gorgolewski, Krzysztof J.
通讯作者：
Gorgolewski, Krzysztof J.