Biocompatibility and thermoplastic formability of Pt-based metallic glasses

Biocompatibility and thermoplastic formability of Pt-based metallic glasses
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铂基金属玻璃的生物相容性和热塑性成型性

DOI:
10.1016/j.matlet.2021.129870
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发表时间:
2021
期刊:
影响因子:
3
通讯作者:
Kumar, G.
Kumar, G.
中科院分区:
材料科学3区
文献类型:
--
作者:
Jagdale, S.;Hu, Q.;Ecker, M.;Kumar, G.

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基于pt的金属玻璃被认为是生物医学上的应用,但镍的存在引起了细胞毒性问题。在这里,我们比较了无镍和含镍pt基金属玻璃的体外细胞反应和热塑性成形性。研究了Pt57.5Cu14.7Ni5.3P22.5、Pt58.7Cu20.3Ag1P20和pt57cu23p20三种玻璃形成成分。无镍Pt-Cu-Ag-P金属玻璃结合了生物相容性和热塑性成型的最佳组合。
Pt-based metallic glasses are considered for biomedical applications, but the presence of Ni poses the cytotoxicity concerns. Here, we compare the in vitro cell response and thermoplastic formability of Ni-free and Ni-containing Pt-based metallic glasses. Three glass forming compositions, Pt57.5Cu14.7Ni5.3P22.5, Pt58.7Cu20.3Ag1P20, and Pt57Cu23P20were investigated. The Ni-free Pt-Cu-Ag-P metallic glass combines the best combination of biocompatibility and thermoplastic forming.
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