International reproducibility of single breathhold T2* MR for cardiac and liver iron assessment among five thalassemia centers.

International reproducibility of single breathhold T2* MR for cardiac and liver iron assessment among five thalassemia centers.
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DOI:
10.1002/jmri.22245
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发表时间:
2010-08
影响因子:
4.4
通讯作者:
Pennell, Dudley J.
Pennell, Dudley J.
中科院分区:
医学2区
文献类型:
--
作者:
Kirk, Paul;He, Taigang;Anderson, Lisa J.;Roughton, Michael;Tanner, Mark A.;Lam, Wynnie W. M.;Au, Wing Y.;Chu, Winnie C. W.;Chan, Godfrey;Galanello, Renzo;Matta, Gildo;Fogel, Mark;Cohen, Alan R.;Tan, Ru San;Chen, Kevin;Ng, Ivy;Lai, Angie;Fucharoen, Suthat;Laothamata, Jiraporn;Chuncharunee, Suporn;Jongjirasiri, Sutipong;Firmin, David N.;Smith, Gillian C.;Pennell, Dudley J.

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在5个国际中心安装标准方法后,检查不同扫描仪的单次屏气T2*技术的可重复性。每个中心最多10名患者进行两次局部扫描,以确定心脏和肝脏T2*的局部研究间重现性,然后空运到中心MR设施,在参考扫描仪上重新扫描,以确定中心间重现性。还评估了所有扫描的观察者间再现性。在49例扫描的患者中,T2*的中心间再现性在心脏为5.9%,在肝脏为5.8%。T2*在心脏和肝脏的局部研究间重复性分别为7.4%和4.6%。T2*在心脏和肝脏的观察者间重现性分别为5.4%和4.4%。这些数据表明,T2* MR可能发展成为组织铁沉着的广泛测试,只要使用明确和批准的成像和分析技术。
To examine the reproducibility of the single breath-hold T2* technique from different scanners, after installation of standard methodology in 5 international centers. Up to 10 patients from each center were scanned twice locally for local interstudy reproducibility of heart and liver T2*, and then flown to a central MR facility to be rescanned on a reference scanner for intercenter reproducibility. Interobserver reproducibility for all scans was also assessed. Of the 49 patients scanned, the intercenter reproducibility for T2* was 5.9% for the heart and 5.8% for the liver. Local interstudy reproducibility for T2* was 7.4% for the heart and 4.6% for the liver. Interobserver reproducibility for T2* was 5.4% for the heart and 4.4% for the liver. These data indicate that T2* MR may be developed into a widespread test for tissue siderosis providing that well defined and approved imaging and analysis techniques are used.
心脏T2*磁共振用于预测Thalassexia Pajor的心脏并发症。
DOI: 10.1161/circulationaha.109.874487
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影响因子: 37.8
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