Natural selection in utero induced by mass layoffs: the hCG evidence.
Natural selection in utero induced by mass layoffs: the hCG evidence.
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DOI：
10.1111/j.1752-4571.2012.00258.x
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发表时间：
2012-12
影响因子：
4.1
通讯作者：
Kharrazi M
中科院分区：
文献类型：
--
作者：
Catalano R;Margerison-Zilko C;Goldman-Mellor S;Pearl M;Anderson E;Saxton K;Bruckner T;Subbaraman M;Goodman J;Epstein M;Currier R;Kharrazi M
进化论与流行病学、人口学和人口内分泌学的研究相结合，表明契约经济通过子宫内的自然选择影响人类的健康和健康。例如，我们知道，当经济意外收缩时，男性胎儿死亡率的增加要高于女性。意外的经济收缩预示着第二性别比例较低；低性别比出生群体的男性平均寿命比高性别比出生群体的男性要长。我们还知道，孕妇血清中人绒毛膜促性腺激素（即 hCG）水平较低可预测胎儿死亡。然而，我们不知道经济紧缩的受孕群体中的男性幸存者是否如理论预测的那样，表现出比其他群体的男性更高的 hCG。我们在 71 个每月受孕队列（包括近 200 万加州新生儿）中证明了这一点。因此，我们在文献中添加了一些内容，表明经济这一我们至少集体行使一定控制力的现象会影响人口健康。我们的研究结果表明，这种效应是通过自然选择产生的——当我们试图解释或改变集体选择如何影响我们的生物学时，我们在很大程度上忽略了这种机制。
Evolutionary theory, when coupled with research from epidemiology, demography, and population endocrinology, suggests that contracting economies affect the fitness and health of human populations via natural selection in utero. We know, for example, that fetal death increases more among males than females when the economy unexpectedly contracts; that unexpected economic contraction predicts low secondary sex ratios; and that males from low sex ratio birth cohorts live, on average, longer than those from high sex ratio cohorts. We also know that low levels of human chorionic gonadotropin (i.e., hCG) measured in the serum of pregnant women predict fetal death. We do not, however, know whether male survivors of conception cohorts subjected to contracting economies exhibit, as theory predicts, higher hCG than those from other cohorts. We show, in 71 monthly conception cohorts including nearly two million California births, that they do. We thereby add to the literature suggesting that the economy, a phenomenon over which we collectively exercise at least some control, affects population health. Our findings imply that the effect arises via natural selection – a mechanism we largely ignore when attempting to explain, or alter, how collective choice affects our biology.
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影响因子：
2.9
作者：
Catalano, Ralph;Zilko, Claire E. Margerison;Bruckner, Tim
通讯作者：
Bruckner, Tim
影响因子：
4.3
作者：
Buss, L;Tolstrup, J;Kjaer, SK
通讯作者：
Kjaer, SK
影响因子：
2
作者：
Catalano, Ralph A.;Saxton, Katherine;Anderson, Elizabeth
通讯作者：
Anderson, Elizabeth
影响因子：
13.7
作者：
Carroll, CD
通讯作者：
Carroll, CD
影响因子：
6.1
作者：
Boklage, CE
通讯作者：
Boklage, CE