Finite-time Lyapunov exponents and metabolic control coefficients for threshold detection of stimulus–response curves
Finite-time Lyapunov exponents and metabolic control coefficients for threshold detection of stimulus–response curves
复制标题
用于刺激反应曲线阈值检测的有限时间李亚普诺夫指数和代谢控制系数
DOI:
10.1080/17513758.2016.1204016
复制
发表时间:
2016
影响因子:
2.8
通讯作者:
S. Siegmund
中科院分区:
文献类型:
--
作者:
L.H. Duc;J. Páez Chávez;D.T. Son;S. Siegmund
In biochemical networks transient dynamics plays a fundamental role, since the activation of signalling pathways is determined by thresholds encountered during the transition from an initial state (eg an initial concentration of a certain protein) to a steady-state. These thresholds can be defined in terms of the inflection points of the stimulus–response curves associated to the activation processes in the biochemical network. In the present work, we present a rigorous discussion as to the suitability of finite-time Lyapunov exponents and metabolic control coefficients for the detection of inflection points of stimulus–response curves with sigmoidal shape.
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影响因子:
4.3
作者:
Millat, Thomas;Bullinger, Eric;Wolkenhauer, Olaf
通讯作者:
Wolkenhauer, Olaf
DOI:
--
发表时间:
2007
期刊:
Brain, Vision, and Artificial Intelligence
影响因子:
--
作者:
P. Lánský;O. Pokora;J. Rospars
通讯作者:
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DOI:
10.1073/pnas.78.11.6840
发表时间:
1981-01-01
期刊:
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES
影响因子:
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作者:
GOLDBETER, A;KOSHLAND, DE
通讯作者:
KOSHLAND, DE
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4.3
作者:
Tiwari A;Ray JC;Narula J;Igoshin OA
通讯作者:
Igoshin OA
DOI:
--
发表时间:
2020
期刊:
影响因子:
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作者:
Saito Takuma;Misaki Kou;Ishizuka Hiroaki;Nagaosa Naoto;村上修一;高坂良史
通讯作者:
高坂良史