Amblyopia, Strabismus and Refractive Errors in Congenital Ptosis: a systematic review and meta-analysis.
Amblyopia, Strabismus and Refractive Errors in Congenital Ptosis: a systematic review and meta-analysis.
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DOI：
10.1038/s41598-018-26671-3
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发表时间：
2018-05-29
影响因子：
4.6
通讯作者：
Ye J
中科院分区：
文献类型：
--
作者：
Wang Y;Xu Y;Liu X;Lou L;Ye J
先天性上睑下垂可能与视觉发育和功能异常有关，包括弱视、斜视和屈光不正。然而，这些异常的患病率估计差异很大。我们进行了系统回顾和荟萃分析，以估计先天性上睑下垂中弱视、斜视和屈光不正的患病率。 Cochrane、Pubmed、Medline、Embase 和 Web of Science 的检索截止时间为 2017 年 7 月。我们使用基于比例方法的随机/固定效应模型来估计患病率。如果 p 值小于 0.1 和/或 I2 大于 50%，则异质性将被视为显着。利用亚组分析、荟萃回归分析和敏感性分析来探讨其潜在来源。总共纳入了从 3,633 篇参考文献中选出的 24 项研究。近视患病率最高，为 30.2% (95%CI 3.0–69.8%)，其次是弱视 22.7% (95%CI 18.5–27.8%)、散光 22.2% (95%CI 7.8–63.1%)、散光 19.6% (95%CI 16.5–23.2%)。斜视，屈光参差为 17.3% (95% CI 13.1–22.9%)，远视为 4.0% (95% CI 1.8–7.1%)。大多数估计都存在显着的异质性。我们的研究结果表明，先天性上睑下垂中弱视、斜视和屈光不正的比例要高得多。这项研究强调了先天性上睑下垂患者早期诊断和及时治疗的重要性。
Congenital ptosis may be associated with abnormalities of visual development and function, including amblyopia, strabismus and refractive errors. However, the prevalence estimates of these abnormalities vary widely. We performed a systematic review and meta-analysis to estimate the prevalence of amblyopia, strabismus and refractive errors in congenital ptosis. Cochrane, Pubmed, Medline, Embase, and Web of Science were searched by July 2017. We used random/fixed effects models based on a proportion approach to estimate the prevalence. Heterogeneity would be considered signifcant if the p values less than 0.1 and/or I2 greater than 50%. Subgroup analyses, meta-regression analyses and sensitivity analyses were utilized to explore the potential sources of it. A total of 24 studies selected from 3,633 references were included. The highest prevalence was revealed for myopia with 30.2% (95%CI 3.0–69.8%), followed by 22.7% (95%CI 18.5–27.8%) for amblyopia, 22.2% (95%CI 7.8–63.1%) for astigmatism, 19.6% (95%CI 16.5–23.2%) for strabismus, 17.3% (95% CI 13.1–22.9%) for anisometropia and 4.0% for hyperopia (95%CI 1.8–7.1%). Significant heterogeneity was identified across most estimates. Our findings suggest that amblyopia, strabismus and refractive errors in congenital ptosis are present in much higher percentage. This study highlights the importance of early diagnosis and timely treatment of patients with congenital ptosis.
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影响因子：
4.2
作者：
Griepentrog, Gregory I.;Mohney, Brian G.
通讯作者：
Mohney, Brian G.
DOI：
10.11604/pamj.2014.19.150.3072
发表时间：
2014
期刊：
The Pan African medical journal
影响因子：
--
作者：
Handor H;Hafidi Z;Bencherif M;Amrani Y;belmokhtar A;Laghmari M;Daoudi R
通讯作者：
Daoudi R
影响因子：
13.7
作者：
Cahill, Kenneth V.;Bradley, Elizabeth A.;Mawn, Louise A.
通讯作者：
Mawn, Louise A.
影响因子：
1.9
作者：
Huo, Lijun;Cui, Dongmei;Zeng, Junwen
通讯作者：
Zeng, Junwen
影响因子：
4.2
作者：
Griepentrog GJ;Diehl N;Mohney BG
通讯作者：
Mohney BG