In vivo proton dosimetry using a MOSFET detector in an anthropomorphic phantom with tissue inhomogeneity.
In vivo proton dosimetry using a MOSFET detector in an anthropomorphic phantom with tissue inhomogeneity.
复制标题
DOI：
10.1120/jacmp.v13i2.3699
复制
发表时间：
2012-03-08
影响因子：
2.1
通讯作者：
Kawashima M
中科院分区：
文献类型：
--
作者：
Kohno R;Hotta K;Matsubara K;Nishioka S;Matsuura T;Kawashima M
当使用金属氧化物半导体场效应晶体管（MOSFET）探测器进行体内质子剂量测定时，探测器的响应强烈依赖于线性能量转移。本研究报告了一种实用的方法来纠正MOSFET响应的线性能量转移依赖通过使用一个简化的蒙特卡罗剂量计算方法（SMC）。使用MOSFET探测器测量了单能质子束在聚乙烯中的深度输出曲线。该曲线用于计算MOSFET的输出分布与SMC。将任意点的输出值与常规方法获得的值进行比较，常规方法使用平行板电离室（PPIC）确定的深度剂量曲线计算质子剂量分布。两个值的比值用于计算任意点处MOSFET响应的校正因子。MOSFET探测器获得的剂量由校正因子和MOSFET原始剂量的乘积确定。当在人体模型中使用MOSFET探测器进行体内质子剂量测定时，校正后的MOSFET剂量与测量误差范围内的结果一致。据我们所知，这是第一个成功的体内质子剂量与MOSFET探测器的报告。PACS编号：87.56. -v
When in vivo proton dosimetry is performed with a metal‐oxide semiconductor field‐effect transistor (MOSFET) detector, the response of the detector depends strongly on the linear energy transfer. The present study reports a practical method to correct the MOSFET response for linear energy transfer dependence by using a simplified Monte Carlo dose calculation method (SMC). A depth‐output curve for a mono‐energetic proton beam in polyethylene was measured with the MOSFET detector. This curve was used to calculate MOSFET output distributions with the SMC . The output value at an arbitrary point was compared with the value obtained by the conventional , which calculates proton dose distributions by using the depth‐dose curve determined by a parallel‐plate ionization chamber (PPIC). The ratio of the two values was used to calculate the correction factor of the MOSFET response at an arbitrary point. The dose obtained by the MOSFET detector was determined from the product of the correction factor and the MOSFET raw dose. When in vivo proton dosimetry was performed with the MOSFET detector in an anthropomorphic phantom, the corrected MOSFET doses agreed with the results within the measurement error. To our knowledge, this is the first report of successful in vivo proton dosimetry with a MOSFET detector. PACS number: 87.56.‐v
登录
查看更多内容
影响因子：
3.5
作者：
Ehringfeld, C;Schmid, S;Georg, D
通讯作者：
Georg, D
DOI：
10.1143/jjap.41.l294
发表时间：
2002-03-01
期刊：
JAPANESE JOURNAL OF APPLIED PHYSICS PART 2-LETTERS
影响因子：
--
作者：
Kohno, R;Sakae, T;Tsunashima, Y
通讯作者：
Tsunashima, Y
影响因子：
3.5
作者：
Hotta, Kenji;Kohno, Ryosuke;Ogino, Takashi
通讯作者：
Ogino, Takashi
DOI：
10.1143/jjap.40.441
发表时间：
2001-01-01
期刊：
JAPANESE JOURNAL OF APPLIED PHYSICS PART 1-REGULAR PAPERS SHORT NOTES & REVIEW PAPERS
影响因子：
--
作者：
Kohno, R;Takada, Y;Yasuoka, K
通讯作者：
Yasuoka, K
影响因子：
3.5
作者：
Nishio, T;Kataoka, S;Ogino, T
通讯作者：
Ogino, T