Whiter matter abnormalities in medication-naive subjects with a single short-duration episode of major depressive disorder.
Whiter matter abnormalities in medication-naive subjects with a single short-duration episode of major depressive disorder.
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曾接受过一次短期重度抑郁症发作的初治受试者的白质异常
DOI：
10.1016/j.pscychresns.2010.09.002
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发表时间：
2011-01-30
影响因子：
2.3
通讯作者：
Liu, Ying
中科院分区：
文献类型：
--
作者：
Wu, Feng;Tang, Yanqing;Xu, Ke;Kong, Lingtao;Sun, Wenge;Wang, Fei;Kong, Dongyan;Li, Yanliang;Liu, Ying
Convergent evidence suggests dysfunction of neural circuitry implicated in major depressive disorder (MDD)(Lockwood et al., 2002; Tekin and Cummings, 2002). Several brain regions, such as the frontal cortex, cingulate cortex, hippocampus, amygdala and parietal lobe have demonstrated involvement in this disorder by both morphometric (Andreescu et al., 2008; Egger et al., 2008; Koolschijn et al., 2009; Tang et al., 2007; Vasic et al., 2008) and functional (Dichter et al., 2009; Matthews et al., 2009; Wagner et al., 2008; Wang et al., 2008a; Wang et al., 2008b; Yang et al., 2009) magnetic resonance imaging (MRI) studies. Additional evidence from postmortem studies further supports the involvement of white matter which providessubstantial connections within those regions in the pathophysiology of MDD. For example, altered deep white matter myeline staining and hyperintensities were observed in the prefrontal cortex in MDD subjects (Regenold et al., 2007; Thomas et al., 2002). Taken together with the findings on oligodendroglial density in the prefrontal cortex in MDD (Uranova et al., 2004), abnormalities of white matter within those circuitries may be directly relevant to the pathophysiology of MDD.
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影响因子：
7.2
作者：
Aizenstein, Howard J.;Butters, Meryl A.;Wu, Minjie;Mazurkewicz, Laura M.;Stenger, V. Andrew;Gianaros, Peter J.;Becker, James T.;Reynolds, Cbarles F., III;Carter, Cameron S.
通讯作者：
Carter, Cameron S.
影响因子：
2.3
作者：
Tang, Yanqing;Wang, Fei;Blumberg, Hilary P.
通讯作者：
Blumberg, Hilary P.
影响因子：
2.3
作者：
Matthews, Scott;Simmons, Alan;Paulus, Martin
通讯作者：
Paulus, Martin
影响因子：
17.7
作者：
Alexopoulos, George S.;Murphy, Christopher F.;Hoptman, Matthew J.
通讯作者：
Hoptman, Matthew J.
影响因子：
6.6
作者：
Kieseppa, Tuula;Eerola, Mervi;Isometsa, Erkki
通讯作者：
Isometsa, Erkki