The role of lipids in corneal diseases and dystrophies: a systematic review.
The role of lipids in corneal diseases and dystrophies: a systematic review.
复制标题
脂质在角膜疾病和营养不良中的作用：一项系统综述。
DOI：
10.1186/s40169-017-0158-1
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发表时间：
2017-12
影响因子：
10.6
通讯作者：
Karamichos D
中科院分区：
文献类型：
--
作者：
Rowsey TG;Karamichos D
Corneal diseases are an extensive cause of blindness worldwide and continue to persist as a challenging public health concern. Recently, various lipid-based therapies have been advocated for the modulation of corneal diseases; however, the number of studies is still very limited. Here we focus on developments and challenges on lipid-based therapies for dry eye disease, diabetic neuropathy, and Fuchs’ endothelial corneal dystrophy. All three diseases are highly prevalent conditions and involve corneal stress and inflammation. Lipid-based therapeutics discussed includes cyclooxygenase inhibitors, essential fatty acids, and resolvin analogs. Lipids also show increasing promise as biomarkers of disease and are explored in this review.
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影响因子：
64.8
作者：
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通讯作者：
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通讯作者：
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4.4
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Bazan, Haydee E. P.