Sleep patterns of patients receiving home parenteral nutrition: A home-based observational study.
Sleep patterns of patients receiving home parenteral nutrition: A home-based observational study.
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DOI：
10.1002/jpen.2346
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发表时间：
2022-09
影响因子：
3.4
通讯作者：
Compher, Charlene
中科院分区：
文献类型：
--
作者：
Dashti, Hassan S.;Godbole, Meghna;Chen, Angela;Mogensen, Kris M.;Leong, Aaron;Burns, David L.;Winkler, Marion F.;Saxena, Richa;Compher, Charlene
关键词：
家庭肠外营养（HPN）支持的患者经常报告睡眠不佳，然而，进行了有限的研究来客观地测量HPN依赖患者的睡眠模式。我们的目的是通过一项以家庭为基础的观察性研究中的7天腕动记录仪来描述HPN患者的睡眠模式。具有临床重要性的睡眠指标来自体动记录仪，包括睡眠持续时间、睡眠效率、入睡潜伏期和入睡后觉醒。参与者还完成了有效的睡眠调查。20例受试者完成了所有研究程序[平均值（标准差）：年龄=51.6（13.9），BMI =21.4 kg/m2（4.6），80%为女性]。人口中位数睡眠持续时间、睡眠效率、入睡潜伏期和入睡后觉醒的四分位距为6.9（1.1）小时，83.3（7.8）%，11.8（7.1）分和57.2分（39.9）分钟，分别有55%，60%，35%和100%的参与者没有达到国家睡眠基金会对这些措施的建议。65%的参与者报告在7天内至少小睡一次。根据失眠严重程度指数，70%的参与者被归类为亚阈值或更严重的失眠。根据匹兹堡睡眠质量指数，85%的人被归类为有严重的睡眠障碍。大多数HPN依赖性患者可能在很大程度上由于难以维持睡眠而导致睡眠中断。这项观察性研究无法阐明HPN导致睡眠不良的程度。解决已知的导致睡眠中断的因素并考虑睡眠干预可能会改善接受HPN的患者的整体生活质量。
Patients supported with home parenteral nutrition (HPN) often report poor sleep, however, limited research has been conducted to objectively measure sleep patterns of HPN-dependent patients. We aimed to characterize the sleep patterns of patients on HPN through 7-day actigraphy in a home-based observational study. Sleep measures of clinical importance were derived from actigraphy including sleep duration, sleep efficiency, sleep onset latency, and wake after sleep onset. Participants also completed validated sleep surveys. 20 participants completed all study procedures [mean (standard deviation): age =51.6 (13.9), BMI =21.4 kg/m2 (4.6), 80% female]. The population median (interquartile range) for sleep duration, sleep efficiency, sleep onset latency, and wake after sleep onset was 6.9 (1.1) hours, 83.3 (7.8) %, 11.8 (7.1) minutes and 57.2 (39.9) minutes, respectively, and 55%, 60%, 35%, and 100% of participants did not meet the recommendations for these measures from the National Sleep Foundation. 65% of participants reported napping at least once during the 7-day period. Based on the Insomnia Severity Index, 70% of participants were classified as having sub-threshold or more severe insomnia. Based on the Pittsburgh Sleep Quality Index, 85% were classified as having significant sleep disturbance. Most HPN-dependent patients likely have disrupted sleep largely driven by difficulty maintaining sleep. The extent to which HPN contributed to poor sleep cannot be elucidated from this observational study. Addressing known factors that contribute to sleep disruption and considering sleep interventions may improve the overall quality of life of patients receiving HPN.
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DOI：
10.1212/con.0000000000000501
发表时间：
2017-08-01
期刊：
Continuum (Minneapolis, Minn.)
影响因子：
--
作者：
Ju, Yo-El S;Videnovic, Aleksandar;Vaughn, Bradley V
通讯作者：
Vaughn, Bradley V
影响因子：
1.6
作者：
Kim, Doo-Young;Park, Hyo-Sik;Kim, Jae-Hyung
通讯作者：
Kim, Jae-Hyung
影响因子：
9.9
作者：
Bertisch, Suzanne M.;Li, Wenyuan;Mittleman, Murray A.
通讯作者：
Mittleman, Murray A.
影响因子：
16.2
作者：
Ayas, NT;White, DP;Hu, FB
通讯作者：
Hu, FB
影响因子：
29.9
作者：
Kocevska, Desana;Lysen, Thom S.;Tiemeier, Henning
通讯作者：
Tiemeier, Henning