Mortality gap for people with bipolar disorder and schizophrenia: UK-based cohort study 2000-2014.
Mortality gap for people with bipolar disorder and schizophrenia: UK-based cohort study 2000-2014.
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DOI:
10.1192/bjp.bp.117.202606
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发表时间:
2017-09
期刊:
影响因子:
--
通讯作者:
Osborn DPJ
中科院分区:
文献类型:
--
作者:
Hayes JF;Marston L;Walters K;King MB;Osborn DPJ
Background Bipolar disorder and schizophrenia are associated with increased mortality relative to the general population. There is an international emphasis on decreasing this excess mortality. Aims To determine whether the mortality gap between individuals with bipolar disorder and schizophrenia and the general population has decreased. Method A nationally representative cohort study using primary care electronic health records from 2000 to 2014, comparing all patients diagnosed with bipolar disorder or schizophrenia and the general population. The primary outcome was all-cause mortality. Results Individuals with bipolar disorder and schizophrenia had elevated mortality (adjusted hazard ratio (HR) = 1.79, 95% CI 1.67–1.88 and 2.08, 95% CI 1.98–2.19 respectively). Adjusted HRs for bipolar disorder increased by 0.14/year (95% CI 0.10–0.19) from 2006 to 2014. The adjusted HRs for schizophrenia increased gradually from 2004 to 2010 (0.11/year, 95% CI 0.04–0.17) and rapidly after 2010 (0.34/year, 95% CI 0.18–0.49). Conclusions The mortality gap between individuals with bipolar disorder and schizophrenia, and the general population is widening.
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DOI:
10.1136/bmj.d3590
发表时间:
2011-06-28
期刊:
BMJ (Clinical research ed.)
影响因子:
--
作者:
Doran T;Kontopantelis E;Valderas JM;Campbell S;Roland M;Salisbury C;Reeves D
通讯作者:
Reeves D
影响因子:
6.6
作者:
Callaghan, Russell C.;Khizar, Anbreen
通讯作者:
Khizar, Anbreen
影响因子:
4.6
作者:
Galletly, Cherrie A.;Foley, Debra L.;Morgan, Vera A.
通讯作者:
Morgan, Vera A.
影响因子:
3.2
作者:
Haw, Camilla;Casey, Deborah;Hawton, Keith
通讯作者:
Hawton, Keith
影响因子:
--
作者:
Druss, BG;Rohrbaugh, RM;Rosenheck, RA
通讯作者:
Rosenheck, RA