Phasic Versus Tonic Irritability: Differential Associations With Attention-Deficit/Hyperactivity Disorder Symptoms.

Phasic Versus Tonic Irritability: Differential Associations With Attention-Deficit/Hyperactivity Disorder Symptoms.
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相性与紧张性易怒:与注意力缺陷/多动障碍症状的差异相关性。

DOI:
10.1016/j.jaac.2020.11.022
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发表时间:
2021-12
影响因子:
13.3
通讯作者:
Kircanski, Katharina
Kircanski, Katharina
中科院分区:
医学1区
文献类型:
--
作者:
Cardinale, Elise M.;Freitag, Gabrielle F.;Brotman, Melissa A.;Pine, Daniel S.;Leibenluft, Ellen;Kircanski, Katharina

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易怒是儿科精神病理学中的一个多方面概念。它被概念化为具有相位维度和主音维度。破坏性情绪失调障碍是由两个维度的存在定义的。严重的易怒或破坏性情绪失调症与注意力缺陷多动障碍(ADHD)高度共病。然而,目前尚不清楚ADHD的存在是否会调节阶段性和紧张性应激的表达。一个数据驱动,潜变量的方法被用来检查易激惹和ADHD症状的transdiagnosis儿科样本(N = 489)与原发性破坏性情绪失调障碍,ADHD,亚临床易激惹症状,或没有诊断。使用潜在特征分析,我们确定了4类:高水平的易怒和ADHD症状,高水平的易怒和中等水平的ADHD症状,中等水平的易怒和高水平的ADHD症状,以及低水平的易怒和ADHD症状。用因子分析法对阶段性应激和紧张性应激进行了操作化。正如预期的那样,以高整体应激为特征的2个潜在类别表现出最高水平的阶段性和紧张性应激。然而,在这2个高易怒等级之间,高度共病ADHD症状与比中度共病ADHD症状显著更大的阶段性易怒相关。相比之下,2个高应激组在紧张性应激水平上没有差异。这些研究结果表明,阶段性,但不是紧张性,易怒有一个显着的关联与ADHD症状,阶段性和紧张性可能是不同的,但高度相关,易怒的尺寸。未来的研究应该调查潜在的机制,这种差异的关联。
Irritability is a multifaceted construct in pediatric psychopathology. It has been conceptualized as having a phasic dimension and a tonic dimension. Disruptive mood dysregulation disorder is defined by the presence of both dimensions. Severe irritability, or disruptive mood dysregulation disorder, is highly comorbid with attention-deficit/hyperactivity disorder (ADHD). However, it is unknown whether the presence of ADHD modulates the expression of phasic and tonic irritability. A data-driven, latent variable approach was used to examine irritability and ADHD symptoms in a transdiagnostic pediatric sample (N = 489) with primary disruptive mood dysregulation disorder, ADHD, subclinical irritability symptoms, or no diagnosis. Using latent profile analyses, we identified 4 classes: high levels of both irritability and ADHD symptoms, high levels of irritability and moderate levels of ADHD symptoms, moderate levels of irritability and high levels of ADHD symptoms, and low levels of both irritability and ADHD symptoms. Confirmatory factor analysis operationalized phasic irritability and tonic irritability. As expected, the 2 latent classes characterized by high overall irritability exhibited the highest levels of both phasic and tonic irritability. However, between these 2 high irritability classes, highly comorbid ADHD symptoms were associated with significantly greater phasic irritability than were moderately comorbid ADHD symptoms. In contrast, the 2 high irritability groups did not differ on levels of tonic irritability. These findings suggest that phasic, but not tonic, irritability has a significant association with ADHD symptoms and that phasic and tonic might be distinct, though highly related, irritability dimensions. Future research should investigate potential mechanisms underlying this differential association.
DOI: 10.1016/j.jad.2016.09.016
发表时间: 2017-07
影响因子: 6.6
作者:
Kircanski K;Zhang S;Stringaris A;Wiggins JL;Towbin KE;Pine DS;Leibenluft E;Brotman MA
通讯作者: Brotman MA
DOI: 10.1207/s15374424jccp2901_4
发表时间: 2000-03-01
期刊: JOURNAL OF CLINICAL CHILD PSYCHOLOGY
影响因子: --
作者:
Maedgen, JW;Carlson, CL
通讯作者: Carlson, CL
DOI: 10.1016/j.brat.2019.04.007
发表时间: 2019-07-01
影响因子: 4.1
作者:
Kircanski, Katharina;Craske, Michelle G.;Brotman, Melissa A.
通讯作者: Brotman, Melissa A.
情绪不稳定是否与多动症儿童的“愤怒/烦躁情绪”、“消极情绪”或其他对立违抗性障碍的子维度不同?
DOI: 10.1177/1087054715624228
发表时间: 2019-06-01
影响因子: 3
作者:
Liu, Lu;Chen, Wai;Wang, Yufeng
通讯作者: Wang, Yufeng
DOI: 10.1097/00004583-199704000-00018
发表时间: 1997-04-01
影响因子: 13.3
作者:
Birmaher, B;Khetarpal, S;Neer, SM
通讯作者: Neer, SM