IL-36 cytokines in autoimmunity and inflammatory disease.
IL-36 cytokines in autoimmunity and inflammatory disease.
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DOI:
10.18632/oncotarget.22814
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发表时间:
2018-01-05
期刊:
影响因子:
--
通讯作者:
Liu D
中科院分区:
文献类型:
--
作者:
Ding L;Wang X;Hong X;Lu L;Liu D
The inteleukin-36 (IL-36) cytokines include IL-36α, IL-36β, IL-36γ and IL-36Ra, which belong to the IL-1 family and exert pro-inflammatory effects on various target cells such as keratinocytes, synoviocytes, dendritic cells and T cells. Emerging evidence has suggested a role of IL-36 in the pathogenesis of many inflammatory diseases. Here, we provide a brief review on the activation of IL-36 family cytokines and their involvement in autoimmunity and inflammatory diseases, which will provide further insights in understanding the functions of IL-36 family cytokines in the pathophysiology of autoimmunity and inflammatory diseases.
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DOI:
10.4049/jimmunol.1003162
发表时间:
2011-02-15
期刊:
Journal of immunology (Baltimore, Md. : 1950)
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发表时间:
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期刊:
Journal of immunology (Baltimore, Md. : 1950)
影响因子:
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