A colorimetric and near-infrared fluorescent turn-on probe for in vitro and in vivo detection of thiophenols
A colorimetric and near-infrared fluorescent turn-on probe for in vitro and in vivo detection of thiophenols
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用于苯硫酚体外和体内检测的比色和近红外荧光开启探针
DOI：
10.1039/c5ay01672j
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发表时间：
2015-09
影响因子：
3.1
通讯作者：
Feng Guoqiang
中科院分区：
文献类型：
--
作者：
Yu Dehuan;Zhai Qisong;Yang Shengjun;Feng Guoqiang
研制了一种用于检测硫酚类化合物的比色近红外荧光探针。该探针具有较大的Stokes位移，对硫酚类化合物具有快速、高选择性和灵敏的检测能力，并具有明显的比色和近红外荧光响应。发现该探针对硫酚的检测限为70 nM。此外，该探针在苯硫酚类化合物的体内外检测中显示出巨大的潜力，成功应用于真实的水样中苯硫酚的定量检测以及活体细胞和斑马鱼中苯硫酚的荧光成像。
A colorimetric and near-infrared fluorescent probe for thiophenols was developed. This new probe features remarkably large Stokes shift, and shows a rapid, highly selective and sensitive detection process for thiophenols with obvious colorimetric and near-infrared fluorescence turn-on responses. The detection limit of this probe for thiophenols was found to be 70 nM. In addition, this probe shows great potential for in vitro and in vivo detection of thiophenols, which was exampled by the successful application of this probe for quantitative detection of thiophenol in real water samples and fluorescence imaging of thiophenol in living cells and zebrafish.
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