Pilot study determining the feasibility of implementing the Disadvantaged Populations eGFR Epidemiology Study (DEGREE) protocol, point-of-care field measurements and a new module on risk factors for chronic kidney disease of unknown origin in Hispanic outdoor workers.
Pilot study determining the feasibility of implementing the Disadvantaged Populations eGFR Epidemiology Study (DEGREE) protocol, point-of-care field measurements and a new module on risk factors for chronic kidney disease of unknown origin in Hispanic outdoor workers.
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DOI：
10.1186/s12882-021-02288-z
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发表时间：
2021-03-12
期刊：
影响因子：
2.3
通讯作者：
Delclos GL
中科院分区：
文献类型：
--
作者：
Figueroa-Solis E;Gimeno Ruiz de Porras D;Delclos GL
在美国西班牙裔户外工作者中现场测试精神障碍人群eGFR流行病学（DEGREE）方案、血清肌酐的户外床旁（POC）检测和一种新的来源不明的慢性肾脏病（CKDu）风险因素模块。在休斯顿（德克萨斯州）采访了50名工人。DEGREE和CKDu问卷在室内完成。在两个时期（2017年11月至12月，2018年4月至5月）在户外完成了用于POC和实验室测定的人体测量学和配对血液样本。管理的程度和CKDu问卷平均10分钟和5分钟，分别与所有的问题很容易理解。我们观察到POC与IDMS肌酐（r = 0.919）和BUN（r = 0.974）之间的高度相关性。当室外温度高于85 °F或低于65 °F时，POC设备将禁用测试;这是可调节的。DEGREE和新的CKDu模块的实现非常简单，也很容易理解。POC设备在现场表现良好，当温度读数超出范围时，对方法进行了一些调整。
To field test the Disadvantaged Populations eGFR Epidemiology (DEGREE) protocol, outdoor point-of-care (POC) testing for serum creatinine, and a new risk factor module on chronic kidney disease of undetermined origin (CKDu) in U.S. outdoor Hispanic workers. Fifty workers were interviewed in Houston (TX). DEGREE and CKDu questionnaires were completed indoors. Anthropometrics and paired blood samples for POC and laboratory assay were completed outdoors over two periods (November–December 2017, April–May 2018). Administration of DEGREE and CKDu questionnaires averaged 10 and 5 min, respectively, with all questions easily understood. We observed high correlations between POC and IDMS creatinine (r = 0.919) and BUN (r = 0.974). The POC device would disable testing when outdoor temperatures were above 85 °F or below 65 °F; this was adjustable. Implementation of DEGREE and the new CKDu module was straightforward and well understood. The POC device performed well in the field, with some adjustment in methods when temperature readings were out of range.
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