Antiallergic activity of Lactobacillus plantarum against peanut allergy in a Balb/c mouse model
Antiallergic activity of Lactobacillus plantarum against peanut allergy in a Balb/c mouse model
复制标题
植物乳杆菌对 Balb/c 小鼠模型花生过敏的抗过敏活性
DOI：
10.1080/09540105.2019.1631261
复制
发表时间：
2019-01
影响因子：
3
通讯作者：
Long Fangyu
中科院分区：
文献类型：
--
作者：
Yang Xin;Liu Ye;Guo Xiaodan;Bai Qiao;Zhu Xiaofan;Ren Hong;Chen Qiwen;Yue Tianli;Long Fangyu
植物乳杆菌的抗过敏活性。plantarum）作为口服益生菌在I型花生变态反应小鼠模型中进行检测。口服L. plantarum恢复了花生过敏原致敏小鼠肠道植物群的恶化状况，减轻了过敏症状，包括腹泻评分、临床评分、血清特异性免疫球蛋白E（IgE）和组胺产生。L.植物管理因此，L.车前草可能通过调节I型变态反应小鼠肠道植物群、肠道细胞因子mRNA的表达而发挥抗变态反应作用，从而减轻变态反应症状，包括血清特异性IgE和临床超敏反应评分。
ABSTRACT Antiallergic activities of Lactobacillus plantarum (L. plantarum) prepared from kimchi as orally administered probiotics were examined in type I peanut allergy mice models. Oral administration with L. plantarum restored the deteriorated profile of enteric flora in mice sensitized with peanut allergen and attenuated allergic symptoms, including diarrhea scores, clinical scores, serum specific immunoglobulin E (IgE) and histamine production. The mRNA expression of interleukin-10 and interferon-γ was suppressed and enhanced, respectively by L. plantarum administration. Thus, L. plantarum probably promoted anti-allergic activities via modulating enteric flora, intestinal cytokines mRNA expression in type I allergic mice, resulting in alleviation of allergic symptoms, including serum specific IgE and clinical hypersensitivity scores.
登录
查看更多内容
影响因子：
5.6
作者：
Huang, Chung-Hsiung;Shen, Chien-Chang;Jan, Tong-Rong
通讯作者：
Jan, Tong-Rong
DOI：
10.1016/j.jaci.2004.02.021
发表时间：
2003-12
期刊：
The Journal of clinical investigation
影响因子：
--
作者：
E. Brandt;R. Strait;D. Hershko;Quan Wang;E. Muntel;Troy A. Scribner;N. Zimmermann;F. Finkelman;M. Rothenberg
通讯作者：
E. Brandt;R. Strait;D. Hershko;Quan Wang;E. Muntel;Troy A. Scribner;N. Zimmermann;F. Finkelman;M. Rothenberg
影响因子：
29
作者：
Donohoe DR;Garge N;Zhang X;Sun W;O'Connell TM;Bunger MK;Bultman SJ
通讯作者：
Bultman SJ
影响因子：
3
作者：
H. Dodo;Damien Marsic;M. Callender;E. Cebert;O. Viquez
通讯作者：
H. Dodo;Damien Marsic;M. Callender;E. Cebert;O. Viquez
影响因子：
4.6
作者：
Tanabe K;Kitagawa E;Wada M;Haraguchi A;Orihara K;Tahara Y;Nakao A;Shibata S
通讯作者：
Shibata S