Tales from the life and lab of a female social neuroscientist.

Tales from the life and lab of a female social neuroscientist.
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DOI:
10.1016/j.cpnec.2023.100202
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发表时间:
2023-11
影响因子:
--
通讯作者:
Parker, Karen J.
Parker, Karen J.
中科院分区:
其他
文献类型:
--
作者:
Parker, Karen J.

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这篇叙述性的回顾描绘了我成为一名社会神经科学家的非常规道路,并描述了我在神经肽生物学领域的研究发现——有些令人困惑,有些偶然,有些关键。我的童年是一个贝尔实验室的“顽童”,我的青春期是一个踢足球的派对女孩,我的研究生生涯是我第一次接触催产素和抗利尿激素的时候。这两种分子立刻吸引住了我的注意力和想象力。25年来,我的研究项目的一个核心目标是更好地了解这些神经肽是如何调节一系列物种的社会功能的(例如,草地田鼠,老鼠,松鼠猴,恒河猴和人类),并从这项工作中转化基本的见解,指导开发新的药物疗法来治疗临床人群的社会障碍。我还讨论了我在STEM领域作为一名女性和母亲的经历,并指出了哪些重要的人物和事件帮助塑造了我的职业生涯和今天的我。这篇叙述性评论的作者描绘了她成为社会神经科学家的非传统职业道路,并确定了帮助塑造她职业生涯的重要人物和事件。她描述了她在神经肽生物学领域的转化研究项目中25年来令人困惑的、偶然的和关键的科学发现。她在STEM中讨论了她作为一名女性和母亲的经历。
This narrative review charts my unconventional path to becoming a social neuroscientist and describes my research findings – some baffling, some serendipitous, some pivotal – in the field of neuropeptide biology. I trace my childhood as a Bell Labs “brat” to my adolescence as a soccer-playing party girl, to my early days as a graduate student, when I first encountered oxytocin and vasopressin. These two molecules instantly captivated – and held – my attention and imagination. For more than 25 years, a core goal of my research program has been to better understand how these neuropeptides regulate social functioning across a range of species (e.g., meadow voles, mice, squirrel monkeys, rhesus monkeys, and humans), and to translate fundamental insights from this work to guide development of novel pharmacotherapies to treat social impairments in clinical populations. I also discuss my experience of being a woman and a mother in STEM, and identify the important people and events which helped shape my career and the scientist I am today. The author of this narrative review charts her unconventional career path to becoming a social neuroscientist, and identifies the important people and events which helped shape her career. She describes a quarter century of baffling, serendipitous, and pivotal scientific findings from her translational research program in the field of neuropeptide biology. She discusses her experience of being a woman and mother in STEM.
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