Microbial dark matter coming to light: challenges and opportunities.
Microbial dark matter coming to light: challenges and opportunities.
复制标题
微生物暗物质的曝光:挑战与机遇
DOI:
10.1093/nsr/nwaa280
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发表时间:
2021-03
影响因子:
20.6
通讯作者:
Li WJ
中科院分区:
文献类型:
--
作者:
Jiao JY;Liu L;Hua ZS;Fang BZ;Zhou EM;Salam N;Hedlund BP;Li WJ
Microbes are the most abundant and diverse cellular life forms on Earth and colonize a wide range of environmental niches. However, more than 99% of bacterial and archaeal species have not been obtained in pure culture [1] and we have only glimpsed the surface of this mysterious microbial world. This is so-called Microbial Dark Matter (MDM): the enormous diversity of yet-uncultivated microbes that microbiologists can only study by using cultivation-independent techniques. Recently, a number of international projects have dramatically increased our understanding of the extent and distribution of microbial diversity, including the Global Catalogue of Microorganisms (GCM), the Genomic Encyclopedia of Bacteria and Archaea (GEBA), the EarthMicrobiome Project (EMP), the Genomic Encyclopedia of Bacteria and Archaea-Microbial Dark Matter (GEBA-MDM) and several primate microbiome projects; however, the functional diversity of MDM is still mysterious. This perspective addresses why MDM deserves scientific effort and illustrates challenges and opportunities in the future study of these enigmas.
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影响因子:
28.3
作者:
Parks, Donovan H.;Rinke, Christian;Tyson, Gene W.
通讯作者:
Tyson, Gene W.
DOI:
10.1099/ijsem.0.004332
发表时间:
2020-11
影响因子:
2.8
作者:
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28.3
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通讯作者:
Banfield, Jillian F.
影响因子:
46.9
作者:
Bowers RM;Kyrpides NC;Stepanauskas R;Harmon-Smith M;Doud D;Reddy TBK;Schulz F;Jarett J;Rivers AR;Eloe-Fadrosh EA;Tringe SG;Ivanova NN;Copeland A;Clum A;Becraft ED;Malmstrom RR;Birren B;Podar M;Bork P;Weinstock GM;Garrity GM;Dodsworth JA;Yooseph S;Sutton G;Glöckner FO;Gilbert JA;Nelson WC;Hallam SJ;Jungbluth SP;Ettema TJG;Tighe S;Konstantinidis KT;Liu WT;Baker BJ;Rattei T;Eisen JA;Hedlund B;McMahon KD;Fierer N;Knight R;Finn R;Cochrane G;Karsch-Mizrachi I;Tyson GW;Rinke C;Genome Standards Consortium;Lapidus A;Meyer F;Yilmaz P;Parks DH;Eren AM;Schriml L;Banfield JF;Hugenholtz P;Woyke T
通讯作者:
Woyke T