At-TAX: a whole genome tiling array resource for developmental expression analysis and transcript identification in Arabidopsis thaliana.

At-TAX: a whole genome tiling array resource for developmental expression analysis and transcript identification in Arabidopsis thaliana.
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DOI:
10.1186/gb-2008-9-7-r112
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发表时间:
2008
期刊:
影响因子:
12.3
通讯作者:
Weigel, Detlef
Weigel, Detlef
中科院分区:
生物学1区
文献类型:
--
作者:
Laubinger, Sascha;Zeller, Georg;Henz, Stefan R.;Sachsenberg, Timo;Widmer, Christian K.;Naouar, Naira;Vuylsteke, Marnik;Schoelkopf, Bernhard;Raetsch, Gunnar;Weigel, Detlef

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提出了基于全基因组平铺阵列的发育表达图谱 At-TAX 以及相关的分析方法。模式生物(包括拟南芥)的基因表达图谱通常是使用以基因为中心的表达阵列创建的。在这里,我们描述了一个综合表达图谱,拟南芥平铺阵列表达(At-TAX),它基于全基因组平铺阵列。我们证明平铺阵列是基因表达分析的准确工具,并鉴定了 1,000 多个未注释的转录区域。基因表达估计、转录区域和平铺探针测量的可视化可在 At-TAX 主页上在线访问。
A developmental expression atlas, At-TAX, based on whole-genome tiling arrays, is presented along with associated analysis methods. Gene expression maps for model organisms, including Arabidopsis thaliana, have typically been created using gene-centric expression arrays. Here, we describe a comprehensive expression atlas, Arabidopsis thaliana Tiling Array Express (At-TAX), which is based on whole-genome tiling arrays. We demonstrate that tiling arrays are accurate tools for gene expression analysis and identified more than 1,000 unannotated transcribed regions. Visualizations of gene expression estimates, transcribed regions, and tiling probe measurements are accessible online at the At-TAX homepage.
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