The effect of egg yolk in diets on anaphylactic arthritis (passive Arthus phenomenon) in the guinea pig.

The effect of egg yolk in diets on anaphylactic arthritis (passive Arthus phenomenon) in the guinea pig.
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蛋黄在饮食中的影响对豚鼠的过敏性关节炎(被动arthus现象)。

DOI:
10.1084/jem.100.5.425
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发表时间:
1954-11-01
期刊:
The Journal of experimental medicine
影响因子:
--
通讯作者:
HANINGER J
HANINGER J
中科院分区:
其他
文献类型:
--
作者:
COBURN AF;GRAHAM CE;HANINGER J

文献摘要

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将全蛋黄作为幼年豚鼠饮食中的补充剂,可以预防过敏性关节炎,具体如下:(a) 通过测量关节肿胀; (b) 某些与二苯胺反应的物质的血清水平升高; (c)通过组织学检查。蛋黄中的活性物质显示在醇溶部分中。迄今为止,用任何已知脂质鉴定活性物质的尝试均未成功。在筛选预防过敏性关节炎的脂质物质时,表明断奶豚鼠是合适的,3周的时间是足够的,并且测试物质可以令人满意地在饮食中施用。
Whole egg yolk incorporated as a supplement in the diet of baby guinea pigs afforded protection against anaphylactic arthritis as determined: (a) by measurement of joint swelling; (b) by the rise in serum level of some substance which reacts with diphenylamine; (c) by histologic examination. The active material in egg yolk was shown to be in the alcohol-soluble fraction. Attempts to identify the active material with any known lipid have to date been unsuccessful. In the screening of lipid substances for protection against anaphylactic arthritis, it is shown that the weanling guinea pig is suitable, that a 3 week period is adequate, and that the test substance can be administered satisfactorily in the diet.
DOI: 10.1172/jci102352
发表时间: 1950-01-01
影响因子: 15.9
作者:
STOLLERMAN, GH;BERNHEIMER, AW
通讯作者: BERNHEIMER, AW
DOI: 10.1097/00000441-195402000-00007
发表时间: 1954-01-01
影响因子: 3.1
作者:
WALLIS, AD
通讯作者: WALLIS, AD
DOI: 10.1001/archpedi.1945.02020230079015
发表时间: 1945-01-01
影响因子: --
作者:
COBURN, AF
通讯作者: COBURN, AF
DOI: 10.1172/jci102408
发表时间: 1950-01-01
影响因子: 15.9
作者:
STOLLERMAN, GH;BERNHEIMER, AW;MACLEOD, CM
通讯作者: MACLEOD, CM
DOI: 10.1172/jci102492
发表时间: 1951-01-01
影响因子: 15.9
作者:
AYALA, W;MOORE, LV;HESS, EL
通讯作者: HESS, EL