Effects of Noise Exposure on the Vestibular System: A Systematic Review.
Effects of Noise Exposure on the Vestibular System: A Systematic Review.
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DOI：
10.3389/fneur.2020.593919
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发表时间：
2020
影响因子：
3.4
通讯作者：
Akin FW
中科院分区：
文献类型：
--
作者：
Stewart CE;Holt AG;Altschuler RA;Cacace AT;Hall CD;Murnane OD;King WM;Akin FW
尽管我们了解噪声引起的听觉系统损伤的影响，但我们对噪声暴露对前庭系统的影响知之甚少。在本文中，我们回顾了噪声引起的周围和中央前庭结构损伤的解剖学、生理学和功能证据。对几种动物模型的形态学研究表明，整个外周前庭系统，特别是耳石器官都有细胞损伤；然而，关于噪声暴露对人类前庭终末器官影响的数据很少。生理学研究证实了前庭通路的破坏，耳石介导的通路比半规管介导的通路影响更大，从而证实了形态学研究。与听觉系统中观察到的暂时阈值变化类似，动物的生理研究表明，噪声引起的前庭损伤后具有恢复能力。人类研究表明，球囊结肠反应的减弱与噪声引起的听力损失的严重程度有关，并且噪声暴露后剂量依赖性前庭缺陷已在动物模型中得到证实。需要进一步的工作来更好地了解噪声引起的动物和人类前庭损伤的生理和功能后果。
Despite our understanding of the impact of noise-induced damage to the auditory system, much less is known about the impact of noise exposure on the vestibular system. In this article, we review the anatomical, physiological, and functional evidence for noise-induced damage to peripheral and central vestibular structures. Morphological studies in several animal models have demonstrated cellular damage throughout the peripheral vestibular system and particularly in the otolith organs; however, there is a paucity of data on the effect of noise exposure on human vestibular end organs. Physiological studies have corroborated morphological studies by demonstrating disruption across vestibular pathways with otolith-mediated pathways impacted more than semicircular canal-mediated pathways. Similar to the temporary threshold shifts observed in the auditory system, physiological studies in animals have suggested a capacity for recovery following noise-induced vestibular damage. Human studies have demonstrated that diminished sacculo-collic responses are related to the severity of noise-induced hearing loss, and dose-dependent vestibular deficits following noise exposure have been corroborated in animal models. Further work is needed to better understand the physiological and functional consequences of noise-induced vestibular impairment in animals and humans.
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影响因子：
3.7
作者：
Holt AG;Bissig D;Mirza N;Rajah G;Berkowitz B
通讯作者：
Berkowitz B
影响因子：
3.7
作者：
Barker M;Solinski HJ;Hashimoto H;Tagoe T;Pilati N;Hamann M
通讯作者：
Hamann M
影响因子：
4.3
作者：
He J;Zhu Y;Aa J;Smith PF;De Ridder D;Wang G;Zheng Y
通讯作者：
Zheng Y
影响因子：
3.4
作者：
Curthoys IS;MacDougall HG;Vidal PP;de Waele C
通讯作者：
de Waele C
影响因子：
5.3
作者：
Dinh CT;Goncalves S;Bas E;Van De Water TR;Zine A
通讯作者：
Zine A