New Developments in Non-invasive Brain Stimulation in Chronic Pain.
New Developments in Non-invasive Brain Stimulation in Chronic Pain.
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DOI：
10.1007/s40141-020-00260-w
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发表时间：
2020-09
影响因子：
1.1
通讯作者：
Greenspan JD
中科院分区：
文献类型：
--
作者：
Meeker TJ;Jupudi R;Lenz FA;Greenspan JD
本综述的目的是总结近年来关于无创脑刺激（NIBS）缓解慢性疼痛综合征患者疼痛的文献。本文回顾了使用经颅直流电（tDCS）和重复经颅磁刺激（rTMS）改善慢性疼痛结果的当前证据。最后，我们向读者介绍新的刺激方法，可能会改善慢性疼痛的治疗效果。虽然tDCS在加拿大和欧盟被批准用于治疗纤维肌痛，但目前在美国没有NIBS方法被批准用于慢性疼痛。增加随机临床试验（RCT）中的样本量似乎是增加对最初有希望结果的信心的最有效方法。资助机构的趋势表明，对NIBS的兴趣和支持有所增加，例如最近美国国立卫生研究院的申请。NIBS结合认知行为疗法和物理疗法可能会提高慢性疼痛的疗效。新的刺激方法，如经颅超声刺激，等待在慢性疼痛的严格研究。靶向运动皮层或左背外侧前额叶皮层的兴奋性NIBS对改善慢性疼痛患者的疼痛具有最大的支持，特别是在慢性重叠疼痛病症（例如纤维肌痛）中。小样本随机对照试验对NIBS干预有效性的信心影响最大。资助机构对NIBS的承诺和应用神经科学中小样本量问题的关注增加，预计将提高对这些相对无副作用的干预措施的信心。
The goal of this review is to present a summary of the recent literature of a non-invasive brain stimulation (NIBS) to alleviate pain in people with chronic pain syndromes. This article reviews the current evidence for the use of transcranial direct current (tDCS) and repetitive transcranial magnetic stimulation (rTMS) to improve outcomes in chronic pain. Finally, we introduce the reader to novel stimulation methods that may improve therapeutic outcomes in chronic pain. While tDCS is approved for treatment of fibromyalgia in Canada and the European Union, no NIBS method is currently approved for chronic pain in the United States. Increasing sample sizes in randomized clinical trials (RCTs) seems the most efficient way to increase confidence in initial promising results. Trends at funding agencies reveal increased interest and support for NIBS such as recent Requests for Application from the National Institutes of Health. NIBS in conjunction with cognitive behavioral therapy and physical therapy may enhance outcomes in chronic pain. Novel stimulation methods, such as transcranial ultrasound stimulation, await rigorous study in chronic pain. Excitatory NIBS targeting motor cortex or left dorsolateral prefrontal cortex has the greatest support for ameliorating pain in chronic pain patients, particularly in Chronic Overlapping Pain Conditions, such as fibromyalgia. Confidence in the efficacy of NIBS interventions is most negatively affected by RCTs with small sample sizes. Increased attention from funding agencies to the promise of NIBS and to the problem of small sample sizes in applied neuroscience is anticipated to improve confidence in these relatively side-effect free interventions.
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经颅磁刺激在治疗慢性广泛疼痛的治疗中：一项随机对照研究。
DOI：
10.1097/yct.0000000000000125
发表时间：
2015-03
期刊：
The journal of ECT
影响因子：
--
作者：
Avery DH;Zarkowski P;Krashin D;Rho WK;Wajdik C;Joesch JM;Haynor DR;Buchwald D;Roy-Byrne P
通讯作者：
Roy-Byrne P
影响因子：
7.7
作者：
Bikson M;Brunoni AR;Charvet LE;Clark VP;Cohen LG;Deng ZD;Dmochowski J;Edwards DJ;Frohlich F;Kappenman ES;Lim KO;Loo C;Mantovani A;McMullen DP;Parra LC;Pearson M;Richardson JD;Rumsey JM;Sehatpour P;Sommers D;Unal G;Wassermann EM;Woods AJ;Lisanby SH
通讯作者：
Lisanby SH
影响因子：
64.8
作者：
BINDMAN, LJ;LIPPOLD, OCJ;REDFEARN, JW
通讯作者：
REDFEARN, JW
影响因子：
7.4
作者：
Attal, Nadine;Ayache, Samar S.;Bouhassira, Didier
通讯作者：
Bouhassira, Didier
影响因子：
7.4
作者：
Bolognini, Nadia;Olgiati, Elena;Fregni, Felipe
通讯作者：
Fregni, Felipe