Influence of age on the association between lifestyle factors and risk of hypertension.
Influence of age on the association between lifestyle factors and risk of hypertension.
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DOI：
10.1016/j.jash.2012.06.002
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发表时间：
2012-07
期刊：
影响因子：
--
通讯作者：
Forman JP
中科院分区：
文献类型：
--
作者：
Cohen L;Curhan GC;Forman JP
Although hypertension is a highly prevalent disease in older populations, risk factors for developing hypertension have been studied primarily in younger cohorts. We sought to determine whether the strength of traditional hypertensive risk factors varied with age. We analyzed the prospective association between five modifiable risk factors and hypertension incidence among 78,590 initially non-hypertensive women of different ages in the Nurses’ Health Study I cohort over 26 years. Older age attenuated the association between incident hypertension and four of five risk factors associated with hypertension in younger women. Persons aged 50 years and under who were low risk for all five risk factor behaviors had a hazard ratio (HR) for incident hypertension of 0.13 (95% CI, 0.03-0.52), compared with others in this age group. In women 61 and older, the HR was 0.62 (95% CI, 0.51-0.75). However, the hypothetical number needed to treat (the number of women needed to join the low risk factor group for a 10 year period to prevent one hypertension case) was similar between the age groups. The fraction of incident hypertension attributable to modifiable lifestyle factors decreases with age. Because the incidence of hypertension is higher in older persons, however, lifestyle modification would hypothetically prevent similar numbers of hypertension cases in younger and older populations.
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影响因子：
4.9
作者：
Casiglia, Edoardo;Tikhonoff, Valerie;Pessina, Achille C.
通讯作者：
Pessina, Achille C.
影响因子：
--
作者：
Lowe, LP;Greenland, P;Stamler, J
通讯作者：
Stamler, J
DOI：
10.1152/ajpendo.2000.279.2.e366
发表时间：
2000-08-01
影响因子：
5.1
作者：
Gallagher, D;Ruts, E;Heymsfield, SB
通讯作者：
Heymsfield, SB
影响因子：
5
作者：
WILLETT, WC;SAMPSON, L;SPEIZER, FE
通讯作者：
SPEIZER, FE
影响因子：
120.7
作者：
Vasan, RS;Beiser, A;Levy, D
通讯作者：
Levy, D