An integrated resource for functional and structural connectivity of the marmoset brain.

An integrated resource for functional and structural connectivity of the marmoset brain.
复制标题

DOI:
10.1038/s41467-022-35197-2
复制
发表时间:
2022-12-01
影响因子:
16.6
通讯作者:
Liu, Cirong
Liu, Cirong
中科院分区:
综合性期刊1区
文献类型:
--
作者:
Tian, Xiaoguang;Chen, Yuyan;Majka, Piotr;Szczupak, Diego;Perl, Yonatan Sanz;Yen, Cecil Chern-Chyi;Tong, Chuanjun;Feng, Furui;Jiang, Haiteng;Glen, Daniel;Deco, Gustavo;Rosa, Marcello G. P.;Silva, Afonso C.;Liang, Zhifeng;Liu, Cirong

文献摘要

参考文献

被引文献

相似文献

结构和功能连接数据的全面整合是准确建模大脑功能所必需的。虽然研究非人类灵长类动物大脑结构连接的资源已经存在,但它们与功能连接数据的整合仍然不可用。在这里,我们提出了一个全面的资源,整合了最广泛的清醒绒猴静息状态功能磁共振成像数据迄今为止(39绒猴,710次运行,12117分钟)与以前发表的细胞水平的神经元示踪数据(52绒猴,143注射)和多分辨率扩散MRI数据集。这些数据的结合使我们能够(1)绘制精细详细的功能性大脑网络和皮层包裹,(2)开发基于深度学习的包裹生成器,保留功能连接的拓扑组织并反映个体差异,以及(3)通过计算建模研究功能连接的结构基础。该资源将能够对结构与功能关系进行建模,并促进灵长类动物大脑的未来比较和转化研究。绘制大脑连接对于解码大脑功能至关重要。在这里,作者提出了一个完整的资源清醒的静息状态功能磁共振成像和神经元跟踪数据的绒猴,以了解大脑连接的结构功能关系。
Comprehensive integration of structural and functional connectivity data is required to model brain functions accurately. While resources for studying the structural connectivity of non-human primate brains already exist, their integration with functional connectivity data has remained unavailable. Here we present a comprehensive resource that integrates the most extensive awake marmoset resting-state fMRI data available to date (39 marmoset monkeys, 710 runs, 12117 mins) with previously published cellular-level neuronal tracing data (52 marmoset monkeys, 143 injections) and multi-resolution diffusion MRI datasets. The combination of these data allowed us to (1) map the fine-detailed functional brain networks and cortical parcellations, (2) develop a deep-learning-based parcellation generator that preserves the topographical organization of functional connectivity and reflects individual variabilities, and (3) investigate the structural basis underlying functional connectivity by computational modeling. This resource will enable modeling structure-function relationships and facilitate future comparative and translational studies of primate brains. Mapping brain connections is critical for decoding brain functions. Here, the authors present an integrated resource of awake resting-state fMRI and neuronal tracing data of marmosets to understand structural-functional relationships of brain connections.
DOI: 10.1016/j.cortex.2018.11.028
发表时间: 2019-09-01
期刊: CORTEX
影响因子: 3.6
作者:
de Schotten, Michel Thiebaut;Croxson, Paula L.;Mars, Rogier B.
通讯作者: Mars, Rogier B.
DOI: 10.1523/jneurosci.3874-05.2006
发表时间: 2006-01-04
影响因子: 5.3
作者:
Achard, S;Salvador, R;Bullmore, ET
通讯作者: Bullmore, ET
DOI: 10.1016/j.neuroimage.2021.118082
发表时间: 2021-08-01
期刊: NeuroImage
影响因子: 5.7
作者:
Autio JA;Zhu Q;Li X;Glasser MF;Schwiedrzik CM;Fair DA;Zimmermann J;Yacoub E;Menon RS;Van Essen DC;Hayashi T;Russ B;Vanduffel W
通讯作者: Vanduffel W
DOI: 10.1073/pnas.0901831106
发表时间: 2009-06-23
影响因子: 11.1
作者:
Deco, Gustavo;Jirsa, Viktor;Koetter, Rolf
通讯作者: Koetter, Rolf
DOI: 10.1038/s41598-017-03073-5
发表时间: 2017-06-08
期刊: SCIENTIFIC REPORTS
影响因子: 4.6
作者:
Deco, Gustavo;Kringelbach, Morten L.;Ritter, Petra
通讯作者: Ritter, Petra