Brain imaging in stroke: insight beyond diagnosis.
Brain imaging in stroke: insight beyond diagnosis.
复制标题
中风中的大脑成像：超出诊断的洞察力。
DOI：
10.1007/s13311-011-0046-0
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发表时间：
2011-07
影响因子：
5.7
通讯作者：
Liebeskind, David S.
中科院分区：
文献类型：
--
作者：
Nour, May;Liebeskind, David S.
关键词：
卒中，无论是出血性还是缺血性，都有可能导致破坏性和使患者衰弱的结局，这不仅从医疗保健的角度来看具有直接影响，而且其影响是长期的，并且影响整个社区。几十年来，成像模式的进步和改进的目标一直是开发最精确，方便，广泛可用和可重复的可解释模式，用于检测中风，不仅在其超急性期，而且是一种能够通过疾病的自然病程预测其演变的方法。诊断是最重要的初始角色之一，成像在识别存在的病理之后完成。然而，成像通过使用成像模式及其精确解释的组合实现了一个更重要的目标，这有助于理解潜在疾病的机制和病理生理学，从而以患者定制的方式指导治疗决策。本文综述了最常用的脑成像方式，计算机断层扫描和磁共振成像，旨在展示其在揭示中风机制，促进中风，并可能指导治疗的动态使用。
Stroke, whether hemorrhagic or ischemic in nature, has the ability to lead to devastating and debilitating patient outcomes, which not only has direct implications from a healthcare standpoint, but its effects are longstanding and they impact the community as a whole. For decades, the goal of advancement and refinement in imaging modalities has been to develop the most precise, convenient, widely available and reproducible interpretable modality for the detection of stroke, not only in its hyperacute phase, but a method to be able to predict its evolution through the natural course of disease. Diagnosis is one of the most important initial roles, which imaging fulfills after the identification of existent pathology. However, imaging fulfills an even more important goal by using a combination of imaging modalities and their precise interpretation, which lends itself to understanding the mechanisms and pathophysiology of underlying disease, and therefore guides therapeutic decision-making in a patient-tailored fashion. This review explores the most commonly used brain imaging modalities, computer tomography, and magnetic resonance imaging, with an aim to demonstrate their dynamic use in uncovering stroke mechanism, facilitating prognostication, and potentially guiding therapy.
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