Screening tests to detect Chlamydia trachomatis and Neisseria gonorrhoeae infections -- 2002
Screening tests to detect Chlamydia trachomatis and Neisseria gonorrhoeae infections -- 2002
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沙眼衣原体和淋病奈瑟菌感染的筛查试验——2002 年
DOI：
--
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发表时间：
2002
期刊：
影响因子：
--
通讯作者：
S. Berman
中科院分区：
文献类型：
--
作者：
Robert E. Johnson;Newhall Wj;Papp;Knapp Js;C. Black;Gift Tl;R. Steece;L. Markowitz;Devine Oj;Walsh Cm;S. Wang;Gunter Dc;Irwin Kl;S. Delisle;S. Berman
自从CDC的1993年指南（CDC，沙眼衣原体感染的预防和管理建议，1993. MMWR 1993;42[No. RR-12]：1-39），核酸扩增试验（NAAT）已被引入作为诊断和治疗C.沙眼和淋病奈瑟菌感染。C的NAAT。沙眼衣原体比以前的测试更敏感。当使用NAAT时，当尿液替代传统拭子样本时，性能上的任何牺牲都是有限的，从而减少了对侵入性程序的依赖，并扩大了可以获得样本的场所。NAAT也可以检测C。沙眼衣原体和N.淋病菌在同一个标本。然而，NAAT通常比以前的测试更昂贵，从经济角度来看，测试性能是一个关键的考虑因素。这份报告更新了1993年关于选择C.沙眼，重点是在美国筛查男性和女性。(In本报告中，筛查是指检测者在没有提示丙肝的症状或体征时。trachomatis或N.淋病感染）。此外，这些指南从经济角度考虑了测试，并扩展了以前的指南，以解决N的检测。淋病和C.沙眼感染由于NAAT的成本增加，某些实验室正在修改制造商的程序，以提高测试灵敏度，而不会产生与NAAT筛查相关的全部成本。这些指南中提到的方法是在使用NAAT进行检测之前合并标本，以及对非NAAT检测结果在灰色区域内的标本进行额外检测。本报告还讨论了在阳性筛查试验后进行额外检测的必要性，以提高最终诊断的特异性。为了准备这些指南，CDC工作人员确定了相关的问题，汇编了1990年或以后发表的相关文献，准备了证据表，并起草了建议。根据其专长或所属学科和组织挑选的顾问审查了建议草案。这些最终指南是CDC工作人员的建议，他们考虑了科学顾问的贡献。这些指南适用于实验室工作者、临床医生和管理人员，他们必须在多种可用的检测方法中进行选择，建立收集和处理标本的标准操作程序，解释实验室报告的检测结果，并为患者提供咨询和治疗。
Since publication of CDC's 1993 guidelines (CDC, Recommendations for the prevention and management of Chlamydia trachomatis infections, 1993. MMWR 1993;42[No. RR-12]:1-39), nucleic acid amplification tests (NAATs) have been introduced as critical new tools to diagnose and treat C. trachomatis and Neisseria gonorrhoeae infections. NAATs for C. trachomatis are substantially more sensitive than previous tests. When using a NAAT, any sacrifice in performance when urine is substituted for a traditional swab specimen is limited, thus reducing dependence on invasive procedures and expanding the venues where specimens can be obtained. NAATs can also detect both C. trachomatis and N. gonorrhoeae organisms in the same specimen. However, NAATs are usually more expensive than previous tests, making test performance from an economic perspective a key consideration. This report updates the 1993 guidelines for selecting laboratory tests for C. trachomatis with an emphasis on screening men and women in the United States. (In this report, screening refers to testing persons in the absence of symptoms or signs indicating C. trachomatis or N. gonorrhoeae infection.) In addition, these guidelines consider tests from an economic perspective and expand the previous guidelines to address detection of N. gonorrhoeae as well as C. trachomatis infections. Because of the increased cost of NAATs, certain laboratories are modifying manufacturers' procedures to improve test sensitivity without incurring the full cost associated with screening with a NAAT. Such approaches addressed in these guidelines are pooling of specimens before testing with a NAAT and additional testing of specimens whose non-NAAT test result is within a gray zone. This report also addresses the need for additional testing after a positive screening test to improve the specificity of a final diagnosis. To prepare these guidelines, CDC staff identified pertinent concerns, compiled the related literature published during 1990 or later, prepared tables of evidence, and drafted recommendations. Consultants, selected for their expertise or disciplinary and organizational affiliations, reviewed the draft recommendations. These final guidelines are the recommendations of CDC staff who considered contributions from scientific consultants. These guidelines are intended for laboratorians, clinicians, and managers who must choose among the multiple available tests, establish standard operating procedures for collecting and processing specimens, interpret test results for laboratory reporting, and counsel and treat patients.
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衣原体感染的选择性筛查：使用哪些标准？
影响因子：
5.5
作者：
Miller,WC;Hoffman,IF;Owen-O'Dowd,J;McPherson,JT;Privette,A;Schmitz,JL;Woodlief,G;Leone,PA
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DOI：
10.1093/infdis/172.5.1411
发表时间：
1995
期刊：
The Journal of infectious diseases
影响因子：
--
作者：
Schachter,J;Moncada,J;Whidden,R;Shaw,H;Bolan,G;Burczak,JD;Lee,HH
通讯作者：
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DOI：
--
发表时间：
1993
期刊：
JAMA : the journal of the American Medical Association
影响因子：
--
作者：
Shafer,MA;Schachter,J;Moncada,J;Keogh,J;Pantell,R;Gourlay,L;Eyre,S;Boyer,CB
通讯作者：
Boyer,CB
遗传性血色病是一种免疫性疾病。
影响因子：
6.5
作者：
Gerhard,GS;TenElshof,AE;Chorney,MJ
通讯作者：
Chorney,MJ