Selective screening for chlamydial infection: which criteria to use?
Selective screening for chlamydial infection: which criteria to use?
复制标题
衣原体感染的选择性筛查：使用哪些标准？
DOI：
10.1016/s0749-3797(99)00146-4
复制
发表时间：
2000
影响因子：
5.5
通讯作者：
Leone,PA
中科院分区：
文献类型：
--
作者：
Miller,WC;Hoffman,IF;Owen-O'Dowd,J;McPherson,JT;Privette,A;Schmitz,JL;Woodlief,G;Leone,PA
背景对性活跃妇女进行沙眼衣原体筛查是发现无症状感染的必要手段。选择性筛查是一种常见的策略，因为在许多情况下，普遍筛查的成本太高。为了指导当地项目选择选择性筛查标准，我们检查了之前提出的沙眼衣原体筛查标准的性能。方法在十个县的公共计划生育和性传播疾病（STD）诊所进行了一项基于诊所的横断面研究。北卡罗来纳州。接受盆腔检查的妇女（n = 4471在计划生育和n = 2201在性病诊所）连续入组。采用敏感性、特异性、所需检测次数和受试者-操作者特征（ROC）分析比较了9套筛选标准（仅包括年龄）。所有妇女进行测试，连接酶链反应检测宫颈标本，以确定沙眼衣原体infection.ResultsThe沙眼衣原体的患病率为7.8%和11.0%，计划生育和性病门诊，分别。发表的标准的灵敏度范围从0.50到0.97。特异性范围为0.05至0.66。在计划生育诊所，最好的标准是检测84%的感染，同时筛查51%的妇女。在性病诊所，同样的标准可以检测出83%的感染，但需要对67%的妇女进行检测。测试年龄≤22岁的妇女将检测到77%的感染计划生育和74%的感染性病诊所，而测试51%和48%的妇女，分别为conclusionsWhen网站的具体标准不能开发，年龄是一个可以接受的战略选择性筛查衣原体感染。
BackgroundScreening sexually active women for Chlamydia trachomatis is necessary to detect asymptomatic infections. Selective screening is a common strategy because universal screening is too costly in many settings. In order to guide local programs in the choice of selective screening criteria, we examined the performance of previously proposed screening criteria for C trachomatis.MethodsA clinic-based, cross-sectional study was conducted in public family planning and sexually transmitted disease (STD) clinics in ten counties in North Carolina. Women (n = 4471 in family planning and n = 2201 in STD clinics) undergoing pelvic examination were enrolled consecutively. Nine sets of screening criteria, including age alone, were compared using sensitivity, specificity, number of tests required and receiver-operator characteristic (ROC) analysis. All women underwent testing with ligase chain reaction assay of cervical specimens to identify C trachomatis infection.ResultsThe prevalence of C trachomatis was 7.8% and 11.0% in family planning and STD clinics, respectively. The sensitivities of published criteria ranged from 0.50 to 0.97. Specificities ranged from 0.05 to 0.66. In family planning clinics, the best performing criteria would detect 84% of infections while screening 51% of women. In STD clinics, the same criteria would detect 83% of infections but require testing 67% of women. Testing women aged ≤22 would detect 77% of infections in family planning and 74% of infections in STD clinics, while testing 51% and 48% of the women, respectively.ConclusionsWhen site-specific criteria cannot be developed, age alone is an acceptable strategy for selective screening for chlamydial infection.
登录
查看更多内容
女性沙眼衣原体感染：是否需要对高流行人群进行普遍筛查？
影响因子：
5
作者：
Hillard Weinstock;Gail Bolan;Robert M. Kohn;Carlos Balladares;Arthur Back;Geraldine Oliva
通讯作者：
Geraldine Oliva
性活跃的年轻女性衣原体感染选择性与普遍筛查的有效性和效率。
影响因子：
--
作者：
J. Sellors;Laura Pickard;Amiram Gafni;Charles H. Goldsmith;D. Jang;Jim Mahony;Max Chernesky
通讯作者：
Max Chernesky
在初级保健妇女人群中选择性筛查沙眼衣原体感染。
影响因子：
5
作者：
Stergachis,A;Scholes,D;Heidrich,FE;Sherer,DM;Holmes,KK;Stamm,WE
通讯作者：
Stamm,WE
1993 年加利福尼亚-墨西哥边境地区西班牙裔妇女的沙眼衣原体感染：在初级保健机构中建立筛查标准
影响因子：
3.1
作者：
R. Gunn;Susan D. Hillis;Philip Shirey;S. Waterman;J. Greenspan
通讯作者：
J. Greenspan
影响因子：
158.5
作者：
Gaydos, CA;Howell, MR;Quinn, TC
通讯作者：
Quinn, TC