Volumetric MRI thermometry using a three-dimensional stack-of-stars echo-planar imaging pulse sequence.

Volumetric MRI thermometry using a three-dimensional stack-of-stars echo-planar imaging pulse sequence.
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DOI:
10.1002/mrm.26862
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发表时间:
2018-04
影响因子:
3.3
通讯作者:
Grissom WA
Grissom WA
中科院分区:
医学3区
文献类型:
--
作者:
Jonathan SV;Grissom WA

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To measure temperature over a large brain volume with fine spatiotemporal resolution. A 3D stack-of-stars echo-planar imaging (3D SoS EPI) sequence combining EPI and radial sampling with golden angle spacing was implemented at 3 Tesla for proton resonance frequency-shift temperature imaging. The sequence acquires a 188×188×43 image matrix with 1.5×1.5×2.75 mm3 spatial resolution. Temperature maps were reconstructed using SENSE image reconstruction followed by the image domain hybrid method, and using the k-space hybrid method. In vivo temperature maps were acquired without heating to measure temperature precision in the brain, and in a phantom during high-intensity focused ultrasound sonication. In vivo temperature standard deviation was less than 1°C at dynamic scan times down to 0.75 seconds. For a given frame rate, scanning at a minimum TR with minimum acceleration yielded the lowest standard deviation. With frame rates around 3.0 seconds, the scan was tolerant to a small number of receive coils, and temperature standard deviation was 48% higher than a standard 2DFT temperature mapping scan, but provided whole-brain coverage. Phantom temperature maps with no visible aliasing were produced for dynamic scan times as short as 0.38 seconds. k-Space hybrid reconstructions were more tolerant to acceleration. 3D SoS EPI temperature mapping provides volumetric brain coverage and fine spatiotemporal resolution.
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