Magnetization spoiling in radial FLASH contrast-enhanced MR digital subtraction angiography.
Magnetization spoiling in radial FLASH contrast-enhanced MR digital subtraction angiography.
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DOI：
10.1002/jmri.23630
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发表时间：
2012-07
影响因子：
4.4
通讯作者：
Carroll, Timothy J.
中科院分区：
文献类型：
--
作者：
Vakil, Parmede;Ansari, Sameer A.;Hurley, Michael C.;Bhat, Himanshu;Batjer, H. Hunt;Bendok, Bernard R.;Eddleman, Christopher S.;Carroll, Timothy J.
通过开发径向FLASH方案，将2D MR数字减影血管造影（DSA）脉冲序列的平面内空间分辨率和图像更新速率分别提高至0.57×0.57 mm和6帧/秒，用于颅内血管疾病应用，并表征文献中先前未描述的新伪影，该伪影在存在此类脉冲序列的情况下出现。脉冲序列进行了优化，伪影的特点是使用模拟和幻影研究。经IRB批准，脉冲序列用于采集健康志愿者和X射线DSA证实的颅内血管疾病患者的时间分辨图像。由于径向波形的性质，伪影来自不均匀的破坏。提出了梯度破坏策略，通过平衡TR间期的梯度矩来消除观察到的伪影。放射状2D MR DSA序列（2.6s时间足迹，6帧/s，滑动窗口因子16，0.57×0.57mm平面内）显示了小血管细节，并证实了颅内血管成像研究中的X线DSA结果。径向2D MR DSA脉冲序列中的适当梯度扰流通过消除环形带状伪影来改善颅内血管描绘。所提出的脉冲序列可以为临床应用的2D MR DSA扫描提供有用的补充。
To increase the in-plane spatial resolution and image update rates of 2D MR Digital Subtraction Angiography (DSA) pulse sequences to 0.57×0.57 mm and 6 frames/s, respectively, for intracranial vascular disease applications by developing a radial FLASH protocol and to characterize a new artifact, not previously described in literature, which arises in the presence of such pulse sequences. The pulse sequence was optimized and artifacts were characterized using simulation and phantom studies. With IRB approval, the pulse sequence was used to acquire time-resolved images from healthy human volunteers and patients with X-ray DSA-confirmed intracranial vascular disease. Artifacts were shown to derive from inhomogenous spoiling due to the nature of radial waveforms. Gradient spoiling strategies were proposed to eliminate the observed artifact by balancing gradient moments across TR intervals. The resulting radial 2D MR DSA sequence (2.6s temporal footprint, 6 frames/s with sliding window factor 16, 0.57×0.57mm in-plane) demonstrated small vessel detail and corroborated X-ray DSA findings in intracranial vascular imaging studies. Appropriate gradient spoiling in radial 2D MR DSA pulse sequences improves intracranial vascular depiction by eliminating circular banding artifacts. The proposed pulse sequence may provide a useful addition to clinically applied 2D MR DSA scans.
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影响因子：
8.3
作者：
Eddleman, Christopher S.;Jeong, Hyun J.;Carroll, Timothy J.
通讯作者：
Carroll, Timothy J.
影响因子：
3.3
作者：
Jeong, Hyun J.;Cashen, Ty A.;Carroll, Timothy J.
通讯作者：
Carroll, Timothy J.
影响因子：
2.8
作者：
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影响因子：
10.6
作者：
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通讯作者：
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影响因子：
3.3
作者：
Griswold, MA;Jakob, PM;Haase, A
通讯作者：
Haase, A