The Pediatric Epilepsy Side Effects Questionnaire: Establishing clinically meaningful change.
The Pediatric Epilepsy Side Effects Questionnaire: Establishing clinically meaningful change.
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DOI：
10.1016/j.yebeh.2015.03.014
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发表时间：
2015-04
期刊：
影响因子：
--
通讯作者：
Modi AC
中科院分区：
文献类型：
--
作者：
Junger KW;Morita D;Modi AC
The present study extends the utility of the Pediatric Epilepsy Side Effects Questionnaire (PESQ) by determining distribution-based minimally clinically important difference (MCID) scores. Participants (N=682) were youth (ages 2–25) with newly diagnosed and chronic epilepsy pooled from research and clinical data in the Comprehensive Epilepsy Center. Caregivers completed the PESQ. Demographic and medical data were extracted from medical chart reviews or via a questionnaire. The MCIDs, which are the standard errors of measurement for each scale, for the entire sample were: Cognitive = 4.66; Motor = 4.67; Behavior = 8.05; General Neurological = 7.41; Weight = 9.58; Total PESQ = 3.25. Additionally, MCIDs for patients with new-onset (<12 months) epilepsy on monotherapy, new-onset epilepsy on polytherapy, chronic epilepsy on monotherapy (>12 months), and chronic epilepsy on polytherapy were calculated. Results from the present study extend the utility of the PESQ by providing clinicians and researchers an enhanced understanding about clinically meaningful changes in side effect profiles across the pediatric epilepsy spectrum. These data can inform clinical decision making for clinicians and researchers.
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影响因子：
--
作者：
Modi, Avani C.;Zeller, Meg H.
通讯作者：
Zeller, Meg H.
DOI：
10.1046/j.1365-2753.2000.00238.x
发表时间：
2000-02-01
影响因子：
2.4
作者：
Wyrwich, KW;Wolinsky, FD
通讯作者：
Wolinsky, FD
影响因子：
16.2
作者：
Hilliard, Marisa E.;Lawrence, Jean M.;Hood, Korey K.
通讯作者：
Hood, Korey K.
影响因子：
5.6
作者：
Wu YP;Follansbee-Junger K;Rausch J;Modi A
通讯作者：
Modi A
影响因子：
7.2
作者：
JUNIPER, EF;GUYATT, GH;GRIFFITH, LE
通讯作者：
GRIFFITH, LE