Temperature sensitivity of negative segregation distortion in Drosophila melanogaster.
Temperature sensitivity of negative segregation distortion in Drosophila melanogaster.
复制标题
果蝇负分离扭曲的温度敏感性。
DOI:
10.1093/genetics/135.3.831
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发表时间:
1993
期刊:
影响因子:
3.3
通讯作者:
Hiraizumi,Y
中科院分区:
文献类型:
--
作者:
Hiraizumi,Y
Previous work has shown that the direction of segregation distortion in the SD (Segregation Distorter) system in Drosophila melanogaster can sometimes be reversed, but this was found only with rather weak distorters and the effect was not large. The present study reports large negative segregation distortion in a strong distorter, SD-72 chromosome. In the presence of a specific X chromosome, supp-X(SD), the proportion, k, of SD-72 chromosomes recovered from the SD-72/cn bw males ranges from 0.99 at 20 degrees to 0.11 at 28.5 degrees, whereas with a standard-X chromosome, k ranges from 0.99 to 0.95 for the same temperature range. The temperature-sensitive period is during spermiogenesis. Using a mating system in which the sperm supply is nearly exhausted, it was shown that the negative distortion at high temperatures is due to an absolute reduction in the number of SD-72 chromosomes and an absolute increase in the number of cn bw chromosomes recovered. After adjusting for non-SD-related temperature effects, the amount of decrease in the number of SD-72 progeny is nearly the same as the amount of increase in the number of cn bw progeny, suggesting that the dysfunction switches from a spermatid carrying one homolog to one carrying the other. Negative distortion requires a radical revision of current hypotheses for the mechanism of segregation distortion and a possible modification of the current model is suggested, based on differential recovery of dysfunction in the two homologs during spermiogenesis.
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DOI:
--
发表时间:
1967
影响因子:
11.1
作者:
D. Hartl;Y. Hiraizumi;J. Crow
通讯作者:
J. Crow
影响因子:
3.3
作者:
Hiraizumi,Y
通讯作者:
Hiraizumi,Y
影响因子:
3.3
作者:
R. Denell;B. H. Judd;R. H. Richardson
通讯作者:
R. H. Richardson
影响因子:
3.3
作者:
D. Hartl
通讯作者:
D. Hartl
影响因子:
3.3
作者:
Y. Hiraizumi;Diana W. Martin;Irene A. Eckstrand
通讯作者:
Irene A. Eckstrand