Transfer Function of Macro-Micro Manipulation on a PDMS Microfluidic Chip
Transfer Function of Macro-Micro Manipulation on a PDMS Microfluidic Chip
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DOI:
10.3390/mi8030080
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发表时间:
2017-03-04
期刊:
影响因子:
3.4
通讯作者:
Kaneko M
中科院分区:
文献类型:
--
作者:
Mizoue K;Teramura K;Tsai CH;Kaneko M
To achieve fast and accurate cell manipulation in a microfluidic channel, it is essential to know the true nature of its input-output relationship. This paper aims to reveal the transfer function of such a micro manipulation controlled by a macro actuator. Both a theoretical model and experimental results for the manipulation are presented. A second-order transfer function is derived based on the proposed model, where the polydimethylsiloxane (PDMS) deformation plays an important role in the manipulation. Experiments are conducted with input frequencies up to 300 Hz. An interesting observation from the experimental results is that the frequency responses of the transfer function behave just like a first-order integration operator in the system. The role of PDMS deformation for the transfer function is discussed based on the experimentally-determined parameters and the proposed model.
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影响因子:
3.4
作者:
Mizoue K;Phan MH;Tsai CD;Kaneko M;Kang J;Chung WK
通讯作者:
Chung WK
影响因子:
7.7
作者:
Avci, Ebubekir;Ohara, Kenichi;Arai, Tatsuo
通讯作者:
Arai, Tatsuo
影响因子:
64.8
作者:
ASHKIN, A;DZIEDZIC, JM;YAMANE, T
通讯作者:
YAMANE, T
影响因子:
2.7
作者:
Chronis, N;Lee, LP
通讯作者:
Lee, LP
影响因子:
6.1
作者:
Bransky, Avishay;Korin, Natanel;Levenberg, Shulamit
通讯作者:
Levenberg, Shulamit