Masticatory biomechanics in the rabbit: a multi-body dynamics analysis.
Masticatory biomechanics in the rabbit: a multi-body dynamics analysis.
复制标题
DOI：
10.1098/rsif.2014.0564
复制
发表时间：
2014-10-06
期刊：
影响因子：
--
通讯作者：
Fagan MJ
中科院分区：
文献类型：
--
作者：
Watson PJ;Gröning F;Curtis N;Fitton LC;Herrel A;McCormack SW;Fagan MJ
多体动力学是一种强有力的工程工具，在颅骨生物力学的仿真和分析中越来越受到欢迎。本文首次将多体动力学应用于兔颅骨的生物力学分析。通过人工解剖和三维成像技术（磁共振成像和微型计算机断层扫描）相结合，构建了一个模型。单个肌肉用多层表示，从而更准确地模拟具有复杂动作线的肌肉纤维。通过比较实验测得的最大切牙咬合力与模型预测的最大切牙咬合力，寻求模型的有效性。磨牙咬合的模拟突出了咀嚼系统改变两个肌肉群的募集的能力，以产生剪切或挤压运动。磨牙剪切能够在所有三个正交方向上处理食物团，而磨牙压碎和切牙咬合主要是垂直方向的。模拟还表明，咀嚼系统适合通过几个周期以低肌肉激活来处理食物，大概是为了防止在重复咀嚼周期期间快速疲劳的快速纤维。我们的研究证明了一个有效的多体动力学模型的有用性，用于研究兔的摄食生物力学，并显示了补充和最终减少体内实验的潜力。
Multi-body dynamics is a powerful engineering tool which is becoming increasingly popular for the simulation and analysis of skull biomechanics. This paper presents the first application of multi-body dynamics to analyse the biomechanics of the rabbit skull. A model has been constructed through the combination of manual dissection and three-dimensional imaging techniques (magnetic resonance imaging and micro-computed tomography). Individual muscles are represented with multiple layers, thus more accurately modelling muscle fibres with complex lines of action. Model validity was sought through comparing experimentally measured maximum incisor bite forces with those predicted by the model. Simulations of molar biting highlighted the ability of the masticatory system to alter recruitment of two muscle groups, in order to generate shearing or crushing movements. Molar shearing is capable of processing a food bolus in all three orthogonal directions, whereas molar crushing and incisor biting are predominately directed vertically. Simulations also show that the masticatory system is adapted to process foods through several cycles with low muscle activations, presumably in order to prevent rapidly fatiguing fast fibres during repeated chewing cycles. Our study demonstrates the usefulness of a validated multi-body dynamics model for investigating feeding biomechanics in the rabbit, and shows the potential for complementing and eventually reducing in vivo experiments.
登录
查看更多内容
影响因子：
2.4
作者：
Curtis, N.;Jones, M. E. H.;Fagan, M. J.
通讯作者：
Fagan, M. J.
影响因子：
2.8
作者：
Gruenheid, T.;Brugman, P.;Langenbach, G. E. J.
通讯作者：
Langenbach, G. E. J.
影响因子：
1.9
作者：
Dimitroulis, George;Slavin, John
通讯作者：
Slavin, John
影响因子：
5.2
作者：
Herrel, A;Spithoven, L;De Vree, F
通讯作者：
De Vree, F
影响因子：
1.9
作者：
FEINBERG, SE;MCDONNELL, EJ
通讯作者：
MCDONNELL, EJ