Epidemiology and classification of dry eye.
Epidemiology and classification of dry eye.
复制标题
干眼症的流行病学和分类。
DOI:
--
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发表时间:
1998
影响因子:
--
通讯作者:
M. Lemp
中科院分区:
文献类型:
--
作者:
M. Lemp
Dry eye, or keratoconjunctivitis sicca (KCS), is a rubric for a number of clinical disease states characterized by disturbances in the pre-ocular tear film resulting in ocular surface disease.1 KCS accounts for a high percentage of patient visits to ophthalmologists, and its treatment has given rise to a pharmaceutical market in the US of over $100 million per year (industry estimates). Approximately 7–10 million Americans currently require the use of artificial tear preparations.2 KCS is associated with a broad spectrum of ocular symptoms ranging from mild transient irritation to persistent irritation, burning, itchiness, redness, pain, ocular fatigue, and vision disturbances.3,4 In its more severe form, Sjogren’s-associated KCS, it is associated with vision-threatening complications including scleritis, corneal ulceration, and secondary bacterial infection.5 Pathophysiologic factors include deficiencies in aqueous tear production, qualitative changes in tear composition, alterations in the oil secretion of the meibomian glands of the eyelids, blinking abnormalities, and inflammatory changes in the ocular surface.6
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影响因子:
4.4
作者:
R. Fox;G. Pearson;J. Vaughan
通讯作者:
R. Fox;G. Pearson;J. Vaughan
影响因子:
13.7
作者:
J. Pepose;R. F. Akata;S. Pflugfelder;W. Voigt
通讯作者:
J. Pepose;R. F. Akata;S. Pflugfelder;W. Voigt
影响因子:
3.1
作者:
Fox,R
通讯作者:
Fox,R
DOI:
--
发表时间:
1985
期刊:
Journal of immunology (Baltimore, Md. : 1950)
影响因子:
--
作者:
Sullivan,DA;Allansmith,MR
通讯作者:
Allansmith,MR
DOI:
--
发表时间:
1987
期刊:
Rheumatic diseases clinics of North America
影响因子:
--
作者:
Fox,RI;Chilton,T;Scott,S;Benton,L;Howell,FV;Vaughan,JH
通讯作者:
Vaughan,JH