Protective effect of allium vegetables against both esophageal and stomach cancer: a simultaneous case-referent study of a high-epidemic area in Jiangsu Province, China.
Protective effect of allium vegetables against both esophageal and stomach cancer: a simultaneous case-referent study of a high-epidemic area in Jiangsu Province, China.
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DOI：
10.1111/j.1349-7006.1999.tb00791.x
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发表时间：
1999-06
期刊：
影响因子：
--
通讯作者：
Tajima K
中科院分区：
文献类型：
--
作者：
Gao CM;Takezaki T;Ding JH;Li MS;Tajima K
为了研究扬中市食管癌和胃癌（SC）的摄入量与食管癌和胃癌（SC）之间的关系，扬中市是中国江苏省食管癌和胃癌的高危地区之一，为了研究扬中市食管癌和胃癌的关系，我们利用组织病理学确诊病例（EC：n = 81，SC：n = 153）和基于人群的参考对象（n = 234）进行了同步病例参考研究。采用问卷调查的方式收集受试者的一般状况、饮食习惯、葱类蔬菜和其他食物的摄入频率、饮茶量、吸烟和饮酒等信息。通过多重逻辑回归模型估计优势比 (OR) 和 95% 置信区间 (CI)。结果显示，经常摄入葱类蔬菜（包括大蒜、洋葱、大葱和韭菜）、生蔬菜、西红柿和四季豆以及喝茶与 EC 和 SC 风险呈负相关。在大蒜、洋葱、大葱和韭菜的最高消费类别（≥1次/周）中，与最低类别（<1次/月）相比，调整后的OR分别为0.30（CI=0.19−0.47）、0.25（CI=0.11−0.54）、0.15（CI=0.08−0.26）和0.57对于 EC，CI 分别为 (CI=0.23−1.42)；对于 SC，分别为 0.31 (CI=0.22−0.44)、0.17 (CI=0.08−0.36)、0.22 (CI=0.15−0.31) 和 0.40 (CI = 0.17−0.94)。本研究的主要结果表明，葱类蔬菜与生蔬菜一样，不仅可能对胃癌而且对食道癌具有重要的预防作用。
To study the relation between allium vegetable intake and cancer of the esophagus (EC) and stomach (SC) in Yangzhong city, which is one of the highest‐risk areas for these cancers in Jiangsu province, China, a simultaneous case‐referent study was conducted using histopathologically confirmed cases (EC: n=81, SC: n=153) and population‐based referents (n=234). A questionnaire was used to collect information on the general status of subjects, their dietary habits, frequency intake of allium vegetables and other foods, tea consumption, smoking and alcohol drinking. The odds ratios (ORs) and 95% confidence intervals (CIs) were estimated by a multiple logistic regression model. The results showed that frequent intake of allium vegetables (including garlic, onion, Welsh onion and Chinese chives), raw vegetables, tomatoes and snap beans, and tea consumption were inversely associated with the risk for EC and SC. In the highest consumption category (≥1 time/ week) of garlic, onion, Welsh onion and Chinese chives, the adjusted ORs compared with the lowest category (<1 time/month) were 0.30 (CI=0.19−0.47), 0.25 (CI=0.11−0.54), 0.15 (CI=0.08−0.26), and 0.57 (CI=0.23−1.42) for EC, and 0.31 (CI=0.22−0.44), 0.17 (CI=0.08−0.36), 0.22 (CI=0.15−0.31) and 0.40 (CI = 0.17−0.94) for SC, respectively. The main results in the present study suggested that allium vegetables, like raw vegetables, may have an important protecting effect against not only stomach cancer, but also esophageal cancer.
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影响因子：
9.7
作者：
HUSSAIN, SP;JANNU, LN;RAO, AR
通讯作者：
RAO, AR
DOI：
10.1016/s1383-5718(97)00116-2
发表时间：
1997-10-24
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作者：
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作者：
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通讯作者：
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影响因子：
2.9
作者：
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通讯作者：
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