Lipid biomarkers: molecular tools for illuminating the history of microbial life
Lipid biomarkers: molecular tools for illuminating the history of microbial life
复制标题
脂质生物标志物:阐明微生物生命史的分子工具
DOI:
10.1038/s41579-021-00636-2
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发表时间:
2022
影响因子:
88.1
通讯作者:
Gold, David A.
中科院分区:
文献类型:
--
作者:
Summons, Roger E.;Welander, Paula V.;Gold, David A.
Fossilized lipids preserved in sedimentary rocks offer singular insights into the Earth’s palaeobiology. These ‘biomarkers’ encode information pertaining to the oxygenation of the atmosphere and oceans, transitions in ocean plankton, the greening of continents, mass extinctions and climate change. Historically, biomarker interpretations relied on inventories of lipids present in extant microorganisms and counterparts in natural environments. However, progress has been impeded because only a small fraction of the Earth’s microorganisms can be cultured, many environmentally significant microorganisms from the past no longer exist and there are gaping holes in knowledge concerning lipid biosynthesis. The revolution in genomics and bioinformatics has provided new tools to expand our understanding of lipid biomarkers, their biosynthetic pathways and distributions in nature. In this Review, we explore how preserved organic molecules provide a unique perspective on the history of the Earth’s microbial life. We discuss how advances in molecular biology have helped elucidate biomarker origins and afforded more robust interpretations of fossil lipids and how the rock record provides vital calibration points for molecular clocks. Such studies are open to further exploitation with the expansion of sequenced microbial genomes in accessible databases.
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影响因子:
64.8
作者:
R. Buick;J. R. Thornett;N. McNaughton;J. B. Smith;M. Barley;M. Savage
通讯作者:
M. Savage
DOI:
10.1073/pnas.1909306116
发表时间:
2019-10
期刊:
Proceedings of the National Academy of Sciences
影响因子:
--
作者:
Z. Zeng;Xiao-Lei Liu;Kristen R Farley;Jeremy H. Wei;W. Metcalf;R. Summons;P. Welander
通讯作者:
Z. Zeng;Xiao-Lei Liu;Kristen R Farley;Jeremy H. Wei;W. Metcalf;R. Summons;P. Welander
影响因子:
3.2
作者:
C. Abella;E. Montesinos;R. Guerrero
通讯作者:
R. Guerrero
DOI:
10.1101/744623
发表时间:
2019-08
期刊:
bioRxiv
影响因子:
--
作者:
A. Zhou;Y. Weber;B. Chiu;F. Elling;A. Cobban;A. Pearson;W. Leavitt
通讯作者:
A. Zhou;Y. Weber;B. Chiu;F. Elling;A. Cobban;A. Pearson;W. Leavitt
影响因子:
5
作者:
CRONIN, JR;PIZZARELLO, S;KRISHNAMURTHY, RV
通讯作者:
KRISHNAMURTHY, RV