Test-retest reliability of peripheral arterial tonometry in the metabolic syndrome.
Test-retest reliability of peripheral arterial tonometry in the metabolic syndrome.
复制标题
DOI：
10.1177/1479164114525971
复制
发表时间：
2014-05
影响因子：
2.4
通讯作者：
Kendall CW
中科院分区：
文献类型：
--
作者：
Sauder KA;West SG;McCrea CE;Campbell JM;Jenkins AL;Jenkins DJ;Kendall CW
Endothelial dysfunction is an important contributor to atherosclerosis and cardiovascular disease. However, routine assessment via angiography or flow-mediated dilation is difficult due to technical limitations. Peripheral arterial tonometry (PAT) is a promising alternative method for non-invasive assessment of endothelial dysfunction. This study assessed the test–retest reliability of PAT in adults with the metabolic syndrome (n = 20) and provides sample size and power estimates for study design. Participants completed five PAT tests each separated by 1 week. The PAT-derived reactive hyperaemia index (RHI) showed robust repeatability (intra-class correlation = 0.74). A parallel-arm study powered at 0.90 would require 22 participants to detect an absolute change in RHI of 0.40 units (equal to ∼25% change in this sample), whereas a crossover study would require 12 participants. In conclusion, we have demonstrated that PAT can be used to assess endothelial dysfunction in adults with the metabolic syndrome as reliably as in healthy samples.
登录
查看更多内容
影响因子：
4.7
作者：
Kendall, C. W. C.;West, S. G.;Jenkins, D. J.
通讯作者：
Jenkins, D. J.
影响因子：
16.2
作者：
Ford, ES
通讯作者：
Ford, ES
影响因子：
3.5
作者：
Onkelinx, Steven;Cornelissen, Veronique;Vanhees, Luc
通讯作者：
Vanhees, Luc
影响因子：
3.5
作者：
Kuvin, Jeffrey T.;Mammen, Anish;Karas, Richard H.
通讯作者：
Karas, Richard H.
影响因子：
8.3
作者：
Pauca, AL;O'Rourke, MF;Kon, ND
通讯作者：
Kon, ND