ENIGMA-anxiety working group: Rationale for and organization of large-scale neuroimaging studies of anxiety disorders.
ENIGMA-anxiety working group: Rationale for and organization of large-scale neuroimaging studies of anxiety disorders.
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ENIGMA-焦虑工作组：焦虑症大规模神经影像研究的基本原理和组织。
DOI：
10.1002/hbm.25100
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发表时间：
2022-01
影响因子：
4.8
通讯作者：
ENIGMA-Anxiety Working Group
中科院分区：
文献类型：
--
作者：
Bas-Hoogendam JM;Groenewold NA;Aghajani M;Freitag GF;Harrewijn A;Hilbert K;Jahanshad N;Thomopoulos SI;Thompson PM;Veltman DJ;Winkler AM;Lueken U;Pine DS;van der Wee NJA;Stein DJ;ENIGMA-Anxiety Working Group
焦虑症是非常普遍和致残的，但似乎特别容易与翻译神经科学方法的调查。神经影像学为我们了解焦虑症的神经生物学提供了信息，但研究受到样本量小、统计功效低以及成像方法异质性的限制。谜-焦虑工作组汇集了来自世界各地的研究人员，以协调一致的努力来应对这些挑战，并产生更强大和可重复的发现。本文阐述的概念和方法通知工作组的工作，并介绍了四个小组研究广泛性焦虑症，惊恐障碍，社交焦虑症，和特定的恐惧症的初步方法。目前，ENIGMA-Anxiety数据库包含来自16个国家和59个机构的100多个独特样本的信息。未来的方向包括研究其他成像方式，整合成像和遗传数据，以及与其他ENIGMA工作组合作。ENIGMA联盟在全球心理健康和临床神经科学的交叉点上创造了协同效应，ENIGMA-Anxiety Working Group将这种方法的承诺扩展到焦虑症的神经影像学研究。焦虑症是非常普遍和致残的，但似乎特别容易与翻译神经科学方法的调查。神经影像学为我们了解焦虑症的神经生物学提供了信息，但研究受到样本量小、统计功效低以及成像方法异质性的限制。谜-焦虑工作组汇集了来自世界各地的研究人员，以协调一致的努力来应对这些挑战，并产生更强大和可重复的发现。ENIGMA联盟在全球心理健康和临床神经科学的交叉点上创造了协同效应，ENIGMA-Anxiety Working Group将这种方法的承诺扩展到焦虑症的神经影像学研究。
Anxiety disorders are highly prevalent and disabling but seem particularly tractable to investigation with translational neuroscience methodologies. Neuroimaging has informed our understanding of the neurobiology of anxiety disorders, but research has been limited by small sample sizes and low statistical power, as well as heterogenous imaging methodology. The ENIGMA‐Anxiety Working Group has brought together researchers from around the world, in a harmonized and coordinated effort to address these challenges and generate more robust and reproducible findings. This paper elaborates on the concepts and methods informing the work of the working group to date, and describes the initial approach of the four subgroups studying generalized anxiety disorder, panic disorder, social anxiety disorder, and specific phobia. At present, the ENIGMA‐Anxiety database contains information about more than 100 unique samples, from 16 countries and 59 institutes. Future directions include examining additional imaging modalities, integrating imaging and genetic data, and collaborating with other ENIGMA working groups. The ENIGMA consortium creates synergy at the intersection of global mental health and clinical neuroscience, and the ENIGMA‐Anxiety Working Group extends the promise of this approach to neuroimaging research on anxiety disorders. Anxiety disorders are highly prevalent and disabling but seem particularly tractable to investigation with translational neuroscience methodologies. Neuroimaging has informed our understanding of the neurobiology of anxiety disorders, but research has been limited by small sample sizes and low statistical power, as well as heterogenous imaging methodology. The ENIGMA‐Anxiety Working Group has brought together researchers from around the world, in a harmonized and coordinated effort to address these challenges and generate more robust and reproducible findings. The ENIGMA consortium creates synergy at the intersection of global mental health and clinical neuroscience, and the ENIGMA‐Anxiety Working Group extends the promise of this approach to neuroimaging research on anxiety disorders.
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影响因子：
7.4
作者：
Alonso J;Liu Z;Evans-Lacko S;Sadikova E;Sampson N;Chatterji S;Abdulmalik J;Aguilar-Gaxiola S;Al-Hamzawi A;Andrade LH;Bruffaerts R;Cardoso G;Cia A;Florescu S;de Girolamo G;Gureje O;Haro JM;He Y;de Jonge P;Karam EG;Kawakami N;Kovess-Masfety V;Lee S;Levinson D;Medina-Mora ME;Navarro-Mateu F;Pennell BE;Piazza M;Posada-Villa J;Ten Have M;Zarkov Z;Kessler RC;Thornicroft G;WHO World Mental Health Survey Collaborators
通讯作者：
WHO World Mental Health Survey Collaborators
影响因子：
4.2
作者：
Bas-Hoogendam, Janna Marie;van Steenbergen, Henk;van der Wee, Nic J. A.
通讯作者：
van der Wee, Nic J. A.
影响因子：
3.1
作者：
Bandelow, Borwin;Baldwin, David;Riederer, Peter
通讯作者：
Riederer, Peter
影响因子：
6.9
作者：
Ball, T. Manber;Ramsawh, H. J.;Campbell-Sills, L.;Paulus, M. P.;Stein, M. B.
通讯作者：
Stein, M. B.
影响因子：
2.9
作者：
Aydin, Semiha;Crone, Mathilde R.;Westenberg, P. Michiel
通讯作者：
Westenberg, P. Michiel